Long-term Outcomes of Glaucoma Surgery in a Real-life Setting: the Agora Registry Study

NCT06829810 | Completed

• 1 other identifier: CHUBX 2023/89
• Study Type: observational
• Target: 1,528
• Locations: 1 country
• Sites: 1

Brief Summary

Retrospective cohort study performed at Bordeaux University Hospital, which aims to analyze long-term safety and efficacy of different techniques of glaucoma surgery including filtering glaucoma surgeries, glaucoma drainage devices or minimally invasive glaucoma surgeries. All patients operated on in the department in the standard of care were proposed to be included in the AGORA registry study. The main outcome will be to define a modelisation of IOP profile based on the surgical technique. Secondary outcomes will be to analyze factors influencing IOP evolution as well as long-term safety and efficacy outcomes of the included surgical techniques.

Conditions

Glaucoma; Ocular Hypertension

Keywords

Intraocular pressure; glaucoma; ocular hypertension; glaucoma surgery; non penetrating deep sclerectomy; trabeculectomy; glaucoma drainage device

Outcome Measures

Primary Outcomes (1)

• Modelisation of IOP profile

  Modelisation of IOP profile of all surgical techniques and additional procedures during the follow-up

  Baseline

Secondary Outcomes (7)

• Modelisation of IOP profile of Non-perforating deep sclerectomy

  Baseline

• Modelisation of IOP profile of Trabeculectomy

  Baseline

• Modelisation of IOP profile of Glaucoma drainage device

  Baseline

• Modelisation of IOP profile of MIGS Istent

  Baseline

• Modelisation of IOP profile of MIGS XEN

  Baseline

Interventions

Modelisation of intraocular pressure profile OTHER

Modelisation of IOP profile of all surgical techniques and additional procedures during the follow-up

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with glaucoma or ocular hypertonia

You may qualify if:

• All patients over the age of 18 with glaucoma or ocular hypertonia treated in the ophthalmology department of Bordeaux University Hospital between 2011 and 2022.

You may not qualify if:

• Refusal to participate
• Patients physically or psychologically unable to understand the study and the research protocol
• Patients under legal protection

Sponsors & Collaborators

• University Hospital, Bordeaux: lead

Study Sites (1)

CHU Bordeaux

Bordeaux, France

Location

MeSH Terms

Conditions

Glaucoma; Ocular Hypertension

Condition Hierarchy (Ancestors)

Eye Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 11, 2025
• First Posted: February 17, 2025
• Study Start: January 15, 2025
• Primary Completion: January 15, 2025
• Study Completion: January 15, 2025
• Last Updated: March 19, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)