Use of Bipolar Diathermy VS Clips in Laparoscopic Appendectomy

NCT06826651 | Not Yet Recruiting DMC

• 1 other identifier: Use of bipolar diathermy
• Study Type: interventional
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Acute Appendicitis is the most frequent acute pathological abdominal illness needing immediate surgery. The laparoscopic appendectomy (LA) has become more popular and is advised as the first course of treatment, particularly for female, obese, and elderly patients.LA can also give surgeons a greater field view and identification of other abdominal organs that can have different pathologies that could mimic the symptoms of acute appendicitis.The most crucial step in preventing major complications such postoperative bleeding, peritonitis, sepsis is sealing the mesoappendix. Due to this circumstance, surgeons are looking for alternative treatments for LA. The best technique for sealing mesoappendix should be affordable, practical, safe, and easy to apply technically. Extracorporeal sliding knots, intracorporeal ligations, endo-loops, nonabsorbable polymer clips (Hem-o-lock clips), hand-made loops, and Ligasure usage, and bipolar cautery division are some of the techniques utilized at LA to seal mesoappendix. According to studies, each of these techniques is secure and practicable.5 In this study, there is a comparative study between using Bipolar diathermy as a source of sealing and other mechanical closure techniques for mesoappendix To assess effect of energy source sealing of mesoappendix by using Bipolar diathermy in comparison to mechanical closure by clips as regard outcome and complications.

Conditions

Laparoscopic Appendectomy; Bipolar Diathermy

Outcome Measures

Primary Outcomes (1)

• intraoperative blood loss

  amount of blood loss will be calcculated by number of towel used and aomunt of blood in sution

  baseline

Study Arms (2)

Group A

EXPERIMENTAL

Laparoscopic appendectomy, using of bipolar diathermy to coagulate mesoappendix

Procedure: laparoscopic appendectomy; Procedure: bipolar diathermy

Group B

EXPERIMENTAL

laparoscopic appendectomy, using surgical clips in closure of mesoappendix

Procedure: laparoscopic appendectomy; Procedure: clips closure

Interventions

laparoscopic appendectomy PROCEDURE

By using laparoscopy, after achieving conclusive identification of the mesoappendix

Group A; Group B

bipolar diathermy PROCEDURE

the mesoappendix coagulated using bipolar diathermy, then cut with scissor.

Group A

clips closure PROCEDURE

mesoappendix will be divided between 3 clips, two placed distally and one proximally. The mesoappendix will be cut in between the clips.

Group B

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All patients admitted to AUH with uncomplicated acute appendicitis or chronic appendicitis
• Age group (18-70)

You may not qualify if:

• patients with complex appendicitis (appendicular mass, abscess, etc).
• patients who had the following conditions: cirrhosis with ascites, abdominal distention, and coagulation disorders, cardiac patients; shock upon arrival, a large ventral hernia, and inflammatory bowel disease

Sponsors & Collaborators

• Assiut University: lead

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor

Study Record Dates

• First Submitted: February 10, 2025
• First Posted: February 14, 2025
• Study Start: March 1, 2025
• Primary Completion (Estimated): March 1, 2028
• Study Completion (Estimated): April 1, 2028
• Last Updated: February 14, 2025

Record last verified: 2025-02