NCT06825000

Brief Summary

The success of psychological therapy can be impacted by patients' beliefs, such as their belief in their own ability to complete therapy and their belief that therapy will work. The goal of this clinical trial is to learn whether and when scientific information about distress and coping can affect beliefs about psychological therapy in adults who experience anxiety. This study will compare two different types of scientific information in a one-hour study. Participants will view educational videos for 30 minutes and complete surveys, including quiz questions about the videos and surveys about their beliefs about psychological therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
262

participants targeted

Target at P75+ for not_applicable anxiety

Timeline
Completed

Started May 2025

Shorter than P25 for not_applicable anxiety

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 23, 2025

Completed
21 days until next milestone

First Posted

Study publicly available on registry

February 13, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

May 21, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 9, 2025

Completed
8 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 17, 2025

Completed
Last Updated

April 14, 2026

Status Verified

April 1, 2026

Enrollment Period

5 months

First QC Date

January 23, 2025

Last Update Submit

April 12, 2026

Conditions

Anxiety

Keywords

beliefsmindsetsexposure therapyneuroscience educationpsycho-educationneuro-education

Outcome Measures

Primary Outcomes (2)

  • Treatment Self-Efficacy

    Measured through self-report on selected items from a version of the validated Bergen Genetic Counseling Self-Efficacy Scale that was previously adapted for treatment self-efficacy in anxiety disorders. The items are rated on a scale of 1-10, with higher numbers indicating greater self-efficacy.

    Immediately before and immediately after watching the videos

  • Treatment Expectancy

    Measured through self-report on a subscale of the validated Credibility/Expectancy Questionnaire, assessing participants' expectation of treatment efficacy. Each item is rated on a scale of 1-9 or 0%-100%, with higher numbers indicating more optimistic expectancy.

    Immediately before and immediately after watching the videos

Secondary Outcomes (1)

  • Treatment Acceptability

    Immediately after watching the videos

Study Arms (2)

Neuro-Ed Group

EXPERIMENTAL

neuroscience education

Behavioral: neuro-education

Psycho-Ed Group

ACTIVE COMPARATOR

psychological science education

Behavioral: psycho-education

Interventions

neuro-educationBEHAVIORAL

30 minutes of videos about the neuroscience of stress, fear, emotion-regulation, and therapy.

Also known as: neuroscience education, Neuro-Ed, NeuroEd
Neuro-Ed Group
psycho-educationBEHAVIORAL

30 minutes of videos about the psychological science of stress, fear, emotion-regulation, and therapy.

Psycho-Ed Group

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Probable anxiety disorder based on the Overall Anxiety Severity and Impairment Scale (OASIS) score
  • Fluent in English
  • Willingness and ability to comply with the protocol
  • Age 18-80
  • The ability to enroll in the study through Prolific.com

You may not qualify if:

  • Having previously seen the study's videos

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California

Irvine, California, 92697, United States

Location

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Golnaz Tabibnia, PhD

    University of California, Irvine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Research Psychologist

Study Record Dates

First Submitted

January 23, 2025

First Posted

February 13, 2025

Study Start

May 21, 2025

Primary Completion

October 9, 2025

Study Completion

October 17, 2025

Last Updated

April 14, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

De-identified IPD that underlie results in a publication may be provided to qualified researchers with academic interest in science education and mental health. Approval of the request and execution of all applicable agreements may be prerequisites to the sharing of data with the requesting party.

Shared Documents
STUDY PROTOCOL, SAP, ICF, ANALYTIC CODE
Time Frame
Data requests can be submitted starting 9 months after article publication, and the data will be made accessible for up to 5 years after study completion.
Access Criteria
Researchers requesting data will first be asked to provide a research proposal. Pending approval of the proposal, they will then be asked to sign a data sharing agreement, which will include restrictions against attempting to identify study participants, on redistribution of the data to third parties, on use of the data for commercial purposes, as well as requirements to electronically secure the data while in use, to destroy the data after analyses are completed, for reporting responsibilities, and for proper acknowledgement of the data resource.

Locations

US(1)