The Pain Perception Threshold in Attention Deficit Disorder With Hyperactivity

NCT06824428 | Completed

• 1 other identifier: 29/12/2024-Number:04
• Study Type: observational
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to evaluate whether the disease subtype affects the presence of chronic pain and pain perception threshold in pediatric patients followed up with the diagnosis of attention deficit and hyperactivity disorder, and to evaluate the factors that may be related to pain perception threshold in disease subtypes.

Conditions

Pain Threshold; Attention Deficit Disorder With Hyperactivity (ADHD)

Outcome Measures

Primary Outcomes (1)

• pressure pain threshold

  The pressure pain threshold will be assessed with a manual pressure algometer (Baseline Dolorimtre®). The patients' pain perception thresholds will be measured bilaterally in the midfrontal region, the midpoint of the trapezius muscle, the lateral epicondyle, the midpoint of the web between the 1st and 2nd fingers, the greater trochanter, and the medial crease of the knee. During the measurement, the 1.52 cm2 flat circular probe of the algometer will be placed on the relevant area and the pressure will be increased by 1 kg/second. Patients will be asked to express their pain by saying 'stop' or raising their hands when they feel slight discomfort. The value for each reference area will be obtained by calculating the arithmetic mean of the paired measurements.

  Baseline

Secondary Outcomes (5)

• Presence of chronic pain

  Baseline

• Pain score

  Baseline

• Duration of chronic pain

  Baseline

• Sociodemographic data of patient

  Baseline

• Sociodemographic data of patient's parents

  Baseline

Study Arms (3)

Predominantly Inattentive

Patients diagnosed with inattentive subtype of attention deficit disorder with hyperactivity according to DSM-5 diagnostic criteria.

Other: Pain perception threshold

Predominantly Hyperactive-Impulsive

Patients diagnosed with hyperactive-impulsive subtype of attention deficit disorder with hyperactivity according to DSM-5 diagnostic criteria.

Other: Pain perception threshold

Inattentive and Hyperactive-Impulsive Combination

Patients diagnosed with mix subtype of attention deficit disorder with hyperactivity according to DSM-5 diagnostic criteria.

Other: Pain perception threshold

Interventions

Pain perception threshold OTHER

The patients' pressure pain threshold will be evaluated with a manual pressure algometer (Baseline Dolorimtre®).The patients' pain perception thresholds will be measured bilaterally in the midfrontal region, the midpoint of the trapezius muscle, the lateral epicondyle, the midpoint of the web between the 1st and 2nd fingers, the greater trochanter, and the medial crease of the knee.

Inattentive and Hyperactive-Impulsive Combination; Predominantly Hyperactive-Impulsive; Predominantly Inattentive

Eligibility Criteria

• Age: 6 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Patients will be selected from among those who apply to Edirne Sultan 1. Murat State Hospital Child and Adolescent Mental Health and Diseases polyclinic.

You may qualify if:

• Diagnosed with attention deficit and hyperactivity disorder according to DSM-5 diagnostic criteria
• Being between the ages of 6-17
• Being at a clinically normal mental level

You may not qualify if:

• Having verbal and visual communication problems
• Having a history of perinatal complications or physical head trauma
• Having comorbid psychiatric disorders other than oppositional defiant disorder and conduct disorder
• Known history of chronic physical and neurological disease (such as cerebral palsy, diabetes, epilepsy, autoimmune diseases, liver and kidney failure)
• Presence of substance or alcohol use disorder
• Having a genetic disorder diagnosis

Sponsors & Collaborators

• Sultan 1. Murat State Hospital: lead

Study Sites (1)

Sultan 1. Murat State Hospital

Edirne, 22030, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• İbrahim Tiryaki, MD

  Sultan 1. Murat State Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: February 7, 2025
• First Posted: February 13, 2025
• Study Start: February 16, 2025
• Primary Completion: December 26, 2025
• Study Completion: December 26, 2025
• Last Updated: December 30, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will share

Locations

TU (1)