Teen Health Choices & Wellness

NCT06822569 | Recruiting

• 2 other identifiers: 2023003584R01DA055600
• Study Type: interventional
• Target: 224
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older. Participants, ages 13 to 16, will be asked to use a smartphone application developed for this research study. Participants will also come to Brown University or meet via video conference to answer questions about specific behaviors, choices, and feelings that may change over time.

Conditions

Health Behavior; Wellness, Psychological; Substance Use

Outcome Measures

Primary Outcomes (1)

• Maximum subjective craving during cannabis cue exposure (rated on a 0 to 10 scale).

  This study utilizes a structured cannabis cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." The specific item to assess positive effects is the question, "How strong is your craving to use cannabis right now" sourced from the Morean' Drug Craving Questionnaire-Now. See reference section.

  Baseline, 1 year, 2 years

Secondary Outcomes (1)

• Maximum subjective positive effects of cannabis use in daily life (rated on a 0 to 10 scale).

  Baseline, 1 year, 2 years

Study Arms (1)

Naturalistic, longitudinal

OTHER

Teenagers ages 13 to 16 years at the time of recruitment.

Other: Cue reactivity paradigm

Interventions

Cue reactivity paradigm OTHER

Participants will be exposed to cues in a fixed sequence while they answer questions about their emotions and thoughts. The cues will include everyday items (e.g., an ink pen) and substance-related items (e.g., a vape pen).

Naturalistic, longitudinal

Eligibility Criteria

• Age: 13 Years - 16 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• be age 13 to 16 years
• engage in a target health behavior on at least one recent occasion
• speak, read, and understand English or Spanish
• live in or near Rhode Island

You may not qualify if:

• lifetime history of moderate or severe substance use disorder or treatment, excluding nicotine use disorder
• current psychotic symptoms or active suicidality (i.e., intent in the past 30 days)

Sponsors & Collaborators

• Brown University: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Brown University School of Public Health

Providence, Rhode Island, 02903, United States

RECRUITING

Related Publications (2)

• Morean ME, de Wit H, King AC, Sofuoglu M, Rueger SY, O'Malley SS. The drug effects questionnaire: psychometric support across three drug types. Psychopharmacology (Berl). 2013 May;227(1):177-92. doi: 10.1007/s00213-012-2954-z. Epub 2012 Dec 28.

  PMID: 23271193 BACKGROUND

• Tiffany ST, Singleton E, Haertzen CA, Henningfield JE. The development of a cocaine craving questionnaire. Drug Alcohol Depend. 1993 Dec;34(1):19-28. doi: 10.1016/0376-8716(93)90042-o.

  PMID: 8174499 BACKGROUND

MeSH Terms

Conditions

Health Behavior; Psychological Well-Being; Substance-Related Disorders

Condition Hierarchy (Ancestors)

Behavior; Personal Satisfaction; Chemically-Induced Disorders; Mental Disorders

Central Study Contacts

Primary Researcher

CONTACT

401-863-6623; teenhealth@brown.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 6, 2025
• First Posted: February 12, 2025
• Study Start: December 27, 2024
• Primary Completion (Estimated): February 1, 2028
• Study Completion (Estimated): February 1, 2028
• Last Updated: April 2, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will share

Locations

US (1)