NCT06822218

Brief Summary

the results of this study may provide an easy non pharmacological modality for dealing with diabetic polyneuropathic pain. Also, the outcome of this study will guide physiotherapists to develop a new noninvasive treatment modality that may improve patient symptoms and promotes their social participation , this in turn may add to clinical role played by therapists in management of diabetic polyneuropathy. In Addition, increased knowledge of the influence of High tone power therapy on neuropathic pain

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 23, 2022

Completed
1 month until next milestone

Study Start

First participant enrolled

January 1, 2023

Completed
2.1 years until next milestone

First Posted

Study publicly available on registry

February 12, 2025

Completed
16 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2025

Completed
Last Updated

February 12, 2025

Status Verified

February 1, 2025

Enrollment Period

2.2 years

First QC Date

November 23, 2022

Last Update Submit

February 11, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Neuropathic pain by DN4 (Douleur Neuropathique en 4 Questions) Questions)

    t is a questionnaire has been developed to facilitate detection of neuropathic pain.total score is 10 .diagnosis of neuropathic pain is 4/10.

    up to 12 weeks

  • Pain pressure threshold algometer

    devices that can be used to identify the pressure and/or force eliciting a pressure-pain threshold. It has been noted in pressure

    up to 12 weeks

Secondary Outcomes (2)

  • Glyclated Haemoglobin Level (HbA1c)

    up to 12 weeks

  • life disability

    up to 12 weeks

Study Arms (2)

High tone power therapy

EXPERIMENTAL

30 type 2 diabetic patients with diabetic polyneuropathy. Theses patients will receive High tone power therapy

Device: high tone power therapy

TENS

ACTIVE COMPARATOR

30 type 2 diabetic patients with diabetic neuropathy. These patients will receive TENS

Device: TENS

Interventions

patients will be assigned into 2 groups with pre and post treatment protocol application. all patients will be thoroughly evaluated before and after treatment protocol application.

High tone power therapy
TENSDEVICE

These patients will receive TENS with applied frequencies range from 2 to 120 Hz. for 3 times per week for 30 minutes every session during 3 months of intervention in addition to medications.

TENS

Eligibility Criteria

Age50 Years - 60 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • The patient selection will be according to the following criteria:
  • Sixty male patients are diagnosed with diabetic polyneuropathy their ages will be ranged from 50-60 years old.
  • All patients are ambulant independently.
  • All patients are under full medical control
  • HbA1c is ranged from 6.5 : 7 %.
  • Patients has diabetes more than 10 years.

You may not qualify if:

  • The participants will be excluded if they meet one of the following criteria:
  • Psychiatric disorders or seizures.
  • Visual and auditory impairment or tremors influencing balance.
  • Other neuromuscular disorders.
  • Foot deformities and ulcers.
  • Lower limb operations.
  • Feverish systemic infection
  • cardiac pacemaker.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Om Elmasryeen Genral Hospital

Giza, Egypt

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus

Interventions

Transcutaneous Electric Nerve Stimulation

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsPhysical Therapy ModalitiesRehabilitationAnalgesiaAnesthesia and Analgesia

Central Study Contacts

zeinab Awadallah, master

CONTACT

Alaa El-Moatasem, lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
senior of physiotherapy

Study Record Dates

First Submitted

November 23, 2022

First Posted

February 12, 2025

Study Start

January 1, 2023

Primary Completion

February 28, 2025

Study Completion

February 28, 2025

Last Updated

February 12, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations