NCT06808659

Brief Summary

This study compares the effects of piriformis stretching and neural mobilization of the sciatic nerve in individuals with piriformis syndrome, a condition that is frequently characterized by hip and buttock pain and discomfort brought on by the piriformis muscle compressing the sciatic nerve.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 2, 2018

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 10, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 28, 2018

Completed
5.9 years until next milestone

First Submitted

Initial submission to the registry

November 29, 2024

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 5, 2025

Completed
Last Updated

February 5, 2025

Status Verified

January 1, 2025

Enrollment Period

6 months

First QC Date

November 29, 2024

Last Update Submit

January 29, 2025

Conditions

Keywords

PhysiotherapyPiriformis StretchingVisual Analog Scale (VAS)Pain ManagementFAIR TestRange of Motion

Outcome Measures

Primary Outcomes (2)

  • Pain Reduction

    Two different interventions were applied in groups after which pain was recorded before and after through visual analogue scale. Highest score means high level of pain and lower score refers to low pain. Maximum score 9 was reported pre study and minmum score 2 was reported after study by both groups on average.

    2 weeks

  • Increase Range of Motion

    Through neural mobilization and piriformis stretching renage of motion was assessed through inclino meter before and after study

    2 weeks

Study Arms (2)

Group A / Sciatic Nerve Mobilization

EXPERIMENTAL

Sciatic Nerve Mobilization was given to group A participants.

Other: Neural Mobilization

Group B / Piriformis Muscle Stretching

EXPERIMENTAL

Piriformis Muscles was stretched in group B participants.

Other: Stretching

Interventions

A total of 20 patients were selected in Group A received neural mobilization of sciatic nerves treatment for 3 days a week for 2 weeks

Also known as: Sciatic Nerve Mobilization
Group A / Sciatic Nerve Mobilization

A total of 20 patients were selected in Group B received stretching of piriformis muscle treatment for 3 days a week for 2 weeks

Also known as: Piriformis Stretching
Group B / Piriformis Muscle Stretching

Eligibility Criteria

Age22 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Positive lasegue sign
  • Positive piriformis sign
  • Tenderness at sciatic notch (over piriformis muscle).

You may not qualify if:

  • Prior surgery of lumbar spine (laminectomy)
  • Unrecognized pelvic fracture
  • Known case of renal stones
  • Disc herniation in lumbar spine
  • Myositis ossificans of piriformis muscle.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Isra Institute of Rehabilitation Sciences

Karachi, Sindh, 74700, Pakistan

Location

Related Publications (7)

  • Othman IK, Raj NB, Siew Kuan C, Sidek S, Wong LS, Djearamane S, Loganathan A, Selvaraj S. Association of Piriformis Thickness, Hip Muscle Strength, and Low Back Pain Patients with and without Piriformis Syndrome in Malaysia. Life (Basel). 2023 May 18;13(5):1208. doi: 10.3390/life13051208.

    PMID: 37240853BACKGROUND
  • Hu YE, Ho GWK, Tortland PD. Deep Gluteal Syndrome: A Pain in the Buttock. Curr Sports Med Rep. 2021 Jun 1;20(6):279-285. doi: 10.1249/JSR.0000000000000848.

    PMID: 34099604BACKGROUND
  • Danazumi MS, Yakasai AM, Ibrahim AA, Shehu UT, Ibrahim SU. Effect of integrated neuromuscular inhibition technique compared with positional release technique in the management of piriformis syndrome. J Osteopath Med. 2021 May 31;121(8):693-703. doi: 10.1515/jom-2020-0327.

    PMID: 34049428BACKGROUND
  • Burke CJ, Walter WR, Adler RS. Targeted Ultrasound-Guided Perineural Hydrodissection of the Sciatic Nerve for the Treatment of Piriformis Syndrome. Ultrasound Q. 2019 Jun;35(2):125-129. doi: 10.1097/RUQ.0000000000000360.

    PMID: 29727344BACKGROUND
  • Shahzad M, Rafique N, Shakil-Ur-Rehman S, Ali Hussain S. Effects of ELDOA and post-facilitation stretching technique on pain and functional performance in patients with piriformis syndrome: A randomized controlled trial. J Back Musculoskelet Rehabil. 2020;33(6):983-988. doi: 10.3233/BMR-181290.

    PMID: 32894238BACKGROUND
  • Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.

    PMID: 36712711BACKGROUND
  • Ankar P, Ratnani GR, Ramteke SU, Jaiswal PR. Effect of Neuromuscular Training and Neurodynamic Solutions for Asymptomatic Prolapsed Intervertebral Disc and Coexisting Piriformis Syndrome in a 19-Year-Old: A Comprehensive Case Report. Cureus. 2024 Jan 27;16(1):e53050. doi: 10.7759/cureus.53050. eCollection 2024 Jan.

Related Links

MeSH Terms

Conditions

Piriformis Muscle SyndromeAgnosia

Condition Hierarchy (Ancestors)

Sciatic NeuropathyMononeuropathiesPeripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesNerve Compression SyndromesNeuralgiaPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPelvic PainPerceptual DisordersNeurobehavioral Manifestations

Study Officials

  • Rabia Khan, Masters of Science

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: In a study involving 40 patients diagnosed with sciatica, researchers aimed to investigate whether neural mobilization of the sciatic nerve or stretching of the piriformis muscle was more effective in treating piriformis syndrome. The patients were divided into two groups, each containing 20 individuals. Group A underwent neural mobilization therapy, while Group B performed piriformis muscle stretches, with both groups receiving treatment three times a week for two weeks. Assessments, including Visual Analog Scale (VAS) for pain, hip range of motion (ROM) in flexion, abduction, and external rotation, as well as the FAIR test, were conducted before and after the interventions.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

November 29, 2024

First Posted

February 5, 2025

Study Start

May 2, 2018

Primary Completion

November 10, 2018

Study Completion

December 28, 2018

Last Updated

February 5, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will not share

Confidentiality

Locations