Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP

NCT06804382 | Not Yet Recruiting

• 1 other identifier: IRB-P00050424
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, 50 pediatricians will participate in academic detailing, an evidence-based, 1-on-1 outreach education technique intended to promote clinician behavior change through brief, highly interactive, and individualized dialogues with trained educators, or "detailers". The goals of this study are to learn about whether this is a practical and acceptable technique, and whether it changes how pediatricians prescribe pre-exposure prophylaxis (PrEP) to adolescents and young adults (AYA) and how patients take it.

Conditions

PrEP; HIV Prevention Program

Keywords

PrEP; STI; AYA; adolescent; hiv prevention; academic detailing

Outcome Measures

Primary Outcomes (4)

• Feasibility

  Feasibility will be assessed using survey question from other academic detailing campaigns and assessed on a 5-point Likert scale. Questions will be: "the key messages are feasible to implement in my practice" (1= not at all through 5= extremely)

  From enrollment to end of study interview at 4 months

• Feasibility

  Feasibility of academic detailing based on number of enrolled providers who complete both academic detailing visits

  From enrollment to end of second academic detailing session at 1 month

• Acceptability

  Acceptability of academic detailing as measured by provider satisfaction with the academic detailing visit. This will be assessed via the Prescriber Satisfaction with Academic Detailing questionnaire (PSAD). Answers are on a 5 point Likert scale (1=not at all through 5=extremely).

  From enrollment to end of second academic detailing visit at 1 month.

• Acceptability

  Acceptability of academic detailing based on completion of academic detailing sessions

  From enrollment to end of second academic detailing session at 1 month

Secondary Outcomes (4)

• Impact of academic detailing on PrEP knowledge and prescribing

  From enrollment to end of study interview at 4 months

• Change in PrEP Prescriptions

  From 6 months prior to enrollment to 6 months after intervention

• HIV Testing

  From 6 months prior to enrollment to 6 months after academic detailing intervention

• Fidelity to intervention

  From enrollment to end of second academic detailing visit at 1 month.

Study Arms (1)

pediatricians

EXPERIMENTAL

Behavioral: Academic detailing

Interventions

Academic detailing BEHAVIORAL

Academic detailing is an evidence-based, 1-on-1 outreach education technique intended to promote clinician behavior change. Information gained during earlier focus groups will be used to develop study-specific materials.

pediatricians

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Primary care provider at one of our 3 study sites (Boston Children's Hospital Adolescent/Young Adult Medicine, Martha Eliot Health Center, Children's Hospital Primary Care Center)

You may not qualify if:

• None

Sponsors & Collaborators

• Boston Children's Hospital: lead

Study Sites (1)

Boston Children's Hospital

Boston, Massachusetts, 02115, United States

Location

Related Publications (1)

• Krakower DS, Naja-Riese GM, Edelstein ZR, Gandhi AD, Wahnich A, Fischer MA. Academic Detailing to Increase Prescribing of HIV Pre-exposure Prophylaxis. Am J Prev Med. 2021 Nov;61(5 Suppl 1):S87-S97. doi: 10.1016/j.amepre.2021.05.030.

  PMID: 34686295 BACKGROUND

MeSH Terms

Conditions

Sexually Transmitted Diseases

Condition Hierarchy (Ancestors)

Communicable Diseases; Infections; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Carly Guss, MD, MPH

CONTACT

617-355-7181; carly.guss@childrens.harvard.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 22, 2025
• First Posted: February 3, 2025
• Study Start (Estimated): April 1, 2027
• Primary Completion (Estimated): March 30, 2030
• Study Completion (Estimated): March 30, 2030
• Last Updated: January 26, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)