Peer to Peer (P2P): Mental Health Interventions With Persons With Substance Use Disorders

NCT06803810 | Completed

• 1 other identifier: 2220242
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study provides substance use and mental health peer support services to address behavioral health disparities in rural areas. Specifically, the project aims to address persistent mental health symptoms, such as anxiety and depression, that become barriers to care for patients working towards long-term recovery from co-occurring mental health and substance use disorders. Participants will be assessed and evaluated for opioid use disorder (OUD), social determinants of health (SDoH), and infectious diseases by a nurse practitioner and a social worker. A certified peer support specialist (CPSS) will provide additional support, connecting patients to sustainable mental health resources and implementing a modified version of the Friendship Bench intervention, which involves six weekly 45-minute problem-solving therapy sessions with the option to participate in six or more peer support sessions. The CPSS will follow the patient for up to 12 weeks.

Conditions

Standard of Care; P2P Intervention

Outcome Measures

Primary Outcomes (1)

• Reduction in depressive symptoms

  Reduce depression symptoms as measured by the PHQ-9

  12 weeks

Study Arms (2)

Standard of Care

NO INTERVENTION

This group will complete a baseline, week 6, and week 12 study visit. Participants will complete research visits (in-person or virtually) at which time they will complete a series of questionnaires.

P2P Intervention

EXPERIMENTAL

This group will complete the same study visits as the standard care group with an additional week 3 visit and 6 CPSS-led therapy intervention sessions. These CPSS led sessions will be completed by the end of the 12week study period. At each study visit you will complete questionnaires.

Behavioral: P2P Intervention

Interventions

P2P Intervention BEHAVIORAL

This group will complete the same study visits as the standard care group with an additional week 3 visit and 6 CPSS-led therapy intervention sessions. These CPSS led sessions will be completed by the end of the 12week study period. At each study visit you will complete questionnaires.

P2P Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of OUD via Diagnostic Statistical Manual (DSM)-V Text Revision (TR)
• Receiving MOUD through the Mobile Recovery Program for at least 3 months
• Age 18 or older
• Moderate to Severe Depression with or without co-occurring anxiety as determined by PHQ-9 conducted during the most recent MRP clinical visit

You may not qualify if:

• Severe cognitive, medical, or psychiatric disability that could impair ability to perform study-related activities as determined by the MRP clinician or principal investigator.
• Unable to read/speak English
• Unable to read and comprehend the consent materials and other study materials
• Current suicidal ideation based on the Patient Health Questionnaire-9

Sponsors & Collaborators

• South Carolina Center for Rural and Primary Healthcare: collaborator
• Prisma Health-Upstate: lead

Study Sites (1)

Prisma Health

Greenville, South Carolina, 29605, United States

Location

Study Officials

• Alain Litwin

  Prisma Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 27, 2025
• First Posted: January 31, 2025
• Study Start: November 11, 2024
• Primary Completion: December 29, 2025
• Study Completion: December 29, 2025
• Last Updated: February 6, 2026

Record last verified: 2026-02

Locations

US (1)