Hyperthyroidism as a Potential Predictive of Worse Outcome of Renal Graft

NCT06794203 | Recruiting

• 1 other identifier: ITTX-21
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The objectives of the study are: to research the association, if any, between the occurrence of thyroid function changes in the immediate post-transplant period and the prognosis of the transplant itself; identify any risk factors for the occurrence of thyroid disorders In the immediate post-transplant period.

Conditions

Kidney Diseases; Kidney Transplant; Hyperthyroidism

Keywords

Hyperthyroidism; Kidney Diseases

Outcome Measures

Primary Outcomes (4)

• Thyroid function

  To research, if any, the alteration of thyroid function in the immediate post-transplant period

  At baseline, then 3-month follow-up after kidney transplantation

• Renal function

  Investigating renal function three months after transplantation.

  At 3-month follow-up after kidney transplantation

• Medical complications

  Investigate about medical complications in the post-transplant period

  Baseline (surgery), at 3-month follow-up after kidney transplantation, at patient discharge

• Survival

  Patient survival at three months after transplantation.

  At 3-month follow-up after kidney transplantation

Study Arms (1)

Kidney transplant patients

All kidney transplant patients at the U.O. of Nephrology, Dialysis and Transplantation directed by Prof. Gaetano La Manna of the Policlinico Sant'Orsola - IRCCS Azienda Ospedaliero Universitaria of Bologna.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All kidney transplant patients at the U.O. of Nephrology, Dialysis and Transplantation directed by Prof. Gaetano La Manna of Policlinico Sant'Orsola - IRCCS Azienda Ospedaliero Universitaria di Bologna.

You may qualify if:

• Subjects transplanted at our Center;
• Subjects whose 3-month follow-up is available;
• Age ≥18 years;
• Availability of clinical and laboratory data regarding thyroid function trends in the immediate post-transplant period (within 30 days after transplantation);
• Subjects giving informed consent to participate.

You may not qualify if:

• None.

Sponsors & Collaborators

• IRCCS Azienda Ospedaliero-Universitaria di Bologna: lead

Study Sites (1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, BO, 40138, Italy

RECRUITING

MeSH Terms

Conditions

Kidney Diseases; Hyperthyroidism

Condition Hierarchy (Ancestors)

Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Thyroid Diseases; Endocrine System Diseases

Study Officials

• Gaetano La Manna, MD

  IRCCS Azienda Ospedaliero-Universitaria di Bologna

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Gaetano La Manna, MD

CONTACT

+39 051 214 4577; gaetano.lamanna@unibo.it

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 30, 2024
• First Posted: January 27, 2025
• Study Start: September 2, 2022
• Primary Completion: July 1, 2025
• Study Completion: July 1, 2025
• Last Updated: January 27, 2025

Record last verified: 2024-12

Locations

IT (1)