Trials Sponsors Conditions Drugs Pricing

Conditions

Malformation Brain

Keywords

Prenatal ultrasounds

Outcome Measures

Primary Outcomes (1)

Correlation between new ultrasound patterns and fetal CNS malformations
Retrospectively analyze ultrasound images of fetuses with established brain malformations
up to 100 weeks

Secondary Outcomes (1)

Comparison of ultrasound patterns found in fetuses with and without CNS malformations
up to 100 weeks

Study Arms (2)

Fetus with CNS malformations

Evaluation of ultrasound images routinely performed during pregnancy in fetuses with brain malformation

Other: Comparison between groups

Fetus withous CNS malformations

Evaluation of ultrasound images routinely performed during pregnancy in healthy fetuses

Other: Comparison between groups

Interventions

Comparison between groupsOther

Ultrasound images acquired during routine ultrasound scans performed in healthy fetuses and in fetuses found to have CNS malformations will be reviewed. Ultrasound images acquired from January 2000 to May 2021 will be analyzed until a sample size of approximately 80 patients is reached, who will be divided into 2 groups: group A (patients whose fetus has CNS malformations) and group B (healthy patients whose fetus has no anatomical CNS abnormalities).

Fetus with CNS malformationsFetus withous CNS malformations

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 45 Years

Sexfemale

Healthy VolunteersNo

Age GroupsAdult (18-64)

Sampling MethodNon-Probability Sample

Study Population

Participants will be divided into 2 groups: group A (patients whose fetus has central nervous system malformations) and group B (healthy patients whose fetus has no anatomical abnormalities of the central nervous system).

You may qualify if:

Women older than 18 years with single pregnancy and fetus with ultrasound diagnosis of central nervous system malformation (group A)

Sponsors & Collaborators

IRCCS Azienda Ospedaliero-Universitaria di Bologna
Otherlead

Study Sites (1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, 40138, Italy

RECRUITING

Gianluigi Pilu, MDCONTACT0512143493 gianluigi.pilu@aosp.bo.it

Study Officials

Gianluigi Pilu, MD
IRCCS Azienda Ospedaliero-Universitaria di Bologna
PRINCIPAL INVESTIGATOR

Central Study Contacts

Gianluigi Pilu, MD

CONTACT

0512143493 gianluigi.pilu@aosp.bo.it

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

December 3, 2024

First Posted

January 23, 2025

Study Start

October 11, 2021

Actual (reported)

Primary Completion

December 31, 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

The Role of Ultrasonography in Pregnancy in the Study of Fetal Central Nervous System Malformations

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

Fetus with CNS malformations

Fetus withous CNS malformations

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

Fetus with CNS malformations

Fetus withous CNS malformations

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations