Effect of Manual Massage Technique on Swelling, Pain and Mouth Opening After Bilateral Lower Third Molar Surgery

NCT06787027 | Completed

• 1 other identifier: 19
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to evaluate the effect of manual lymphatic drainage on pain, edema and trismus after impacted mandibular third molar surgery.

Conditions

Impacted Third Molar Tooth; Swelling/ Edema; Pain; Trismus

Keywords

impacted lower third molar; 3dMD; Manual Lymphatic Drainage; edema

Outcome Measures

Primary Outcomes (1)

• postoperative facial swelling

  Facial swelling T0-T1 and T0-T2 scans are opened and superimposed through three reference points: endocanthion left (inner most point on commissure of left eye fissure), endocanthion right (inner most point on commissure of right eye fissure) and subnasale (mid point of columella). After matching, the swelling was calculated by selecting the area of the swelling and subtracting the two images.

  one week

Secondary Outcomes (2)

• Pain

  one week

• Mouth opening

  one week

Study Arms (2)

Manual Lymphatic Drainage technique

EXPERIMENTAL

Following the morning surgery, MLD therapy was administered in the afternoon of the same day by a professional physiotherapist

Procedure: Manual Lymphatic Drainage technique; Procedure: Conventional Treatment group

Conventional treatment

EXPERIMENTAL

Postoperatively, patients were prescribed antibiotics (amoxicillin with clavulanic acid, 1 g, twice daily), analgesics (paracetamol, 500 mg, twice daily), and mouthwash (chlorhexidine gluconate, three times daily) for five days.

Procedure: Manual Lymphatic Drainage technique; Procedure: Conventional Treatment group

Interventions

Manual Lymphatic Drainage technique PROCEDURE

Following the morning surgery, manual lymphatic drainage therapy was administered in the afternoon of the same day by a professional physiotherapist.

Conventional treatment; Manual Lymphatic Drainage technique

Conventional Treatment group PROCEDURE

patients were prescribed antibiotics (amoxicillin with clavulanic acid, 1 g, twice daily), analgesics (paracetamol, 500 mg, twice daily), and mouthwash (chlorhexidine gluconate, three times daily) for five days. Cold application was recommended to all patients.

Conventional treatment; Manual Lymphatic Drainage technique

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• good general health conditions;
• presence of bilateral and symmetrical impacted third molars (according to the classifications of Winter and Pell and Gregory);

You may not qualify if:

• no clinical evidence of major facial asymmetry;
• use of medication that would influence or alter wound healing;
• temporomandibular joint disorder history;
• smoking

Sponsors & Collaborators

• Izmir Katip Celebi University: lead

Study Sites (1)

Izmir Katip Çelebi University

Izmir, Çiğli, 35575, Turkey (Türkiye)

Location

Related Publications (1)

• Ulu M, Unal N, Sahin O, Kayali Y. Evaluation of the effect of manual lymphatic drainage method on edema, pain and trismus after impacted bilateral mandibular third molar surgery: a randomized clinical trial. BMC Oral Health. 2025 Mar 26;25(1):438. doi: 10.1186/s12903-025-05817-6.

  PMID: 40140780 DERIVED

MeSH Terms

Conditions

Edema; Pain; Trismus

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurologic Manifestations; Spasm; Neuromuscular Manifestations; Nervous System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: Split-mouth model

Study Record Dates

• First Submitted: January 16, 2025
• First Posted: January 22, 2025
• Study Start: March 1, 2018
• Primary Completion: September 1, 2018
• Study Completion: September 1, 2018
• Last Updated: January 22, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)