NCT06784375

Brief Summary

This project will compare medical nutrition therapy personalized by continuous glucose monitor (CGM) feedback to control interventions in participants with type 2 diabetes mellitus (T2DM).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable type-2-diabetes

Timeline
15mo left

Started Jul 2025

Typical duration for not_applicable type-2-diabetes

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress42%
Jul 2025Aug 2027

First Submitted

Initial submission to the registry

January 14, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 20, 2025

Completed
6 months until next milestone

Study Start

First participant enrolled

July 14, 2025

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

July 15, 2025

Status Verified

July 1, 2025

Enrollment Period

2 years

First QC Date

January 14, 2025

Last Update Submit

July 14, 2025

Conditions

Keywords

Type 2 DiabetesNutritionCGM

Outcome Measures

Primary Outcomes (1)

  • Hemoglobin A1c

    Measure of blood glucose control

    12 weeks

Study Arms (4)

Unblinded CGM/Nutrition Therapy

EXPERIMENTAL
Behavioral: Unblinded CGM/Nutrition Therapy

Blinded CGM/Nutrition Therapy

EXPERIMENTAL
Behavioral: Blinded CGM/Nutrition Therapy

Unblinded CGM/No Nutrition Therapy

EXPERIMENTAL
Behavioral: Unblinded CGM/No Nutrition Therapy

Blinded CGM/No Nutrition Therapy

EXPERIMENTAL
Behavioral: Blinded CGM/No Nutrition Therapy

Interventions

Personalized nutrition counseling based on CGM data

Unblinded CGM/Nutrition Therapy

Standard nutrition education which does not incorporate CGM data

Blinded CGM/Nutrition Therapy

CGM and general diabetes education (no nutrition education)

Unblinded CGM/No Nutrition Therapy

General diabetes education (no nutrition education)

Blinded CGM/No Nutrition Therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • at least 18 years of age
  • previous diagnosis of T2DM
  • HbA1c of 6.8-8.5%

You may not qualify if:

  • type 1 diabetes mellitus
  • treatment with insulin, sulfonylurea, or meglitinide
  • use of nondiabetic medications that affect blood glucose control (such as corticosteroids)
  • BMI \<25 kg/m2 or \<23 kg/m2 for participants who self-identify as Asian
  • weight change \>5 pounds in the 3 months prior to study enrollment
  • estimated glomerular filtration rate \<60 ml/minute/1.73 m2
  • pregnancy or immediate plans to become pregnant 8) breastfeeding 9) anemia (which would affect measurement of HbA1c) 10) changes to glucose lowering medications, including change in dose, in the 3 months prior to enrollment 11) presence of any disease that would make adherence to the protocol difficult."

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Minnesota

Minneapolis, Minnesota, 55455, United States

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Anne Bantle

    University of Minnesota

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Model Details: Prospective Randomized Trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 14, 2025

First Posted

January 20, 2025

Study Start

July 14, 2025

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

July 15, 2025

Record last verified: 2025-07

Locations