NCT06781749

Brief Summary

The goal of this clinical trial is to learn if hearing devices, like hearing aids, affect social and cognitive function of older adults. The main questions the researchers want to answer are:

  • How social are older adults with hearing loss before and after using hearing devices?
  • How well do older adults with hearing loss think before and after using hearing devices?
  • For older adults who have hearing loss and use hearing devices, do changes in social interaction explain changes in how well they think (cognitive function)?
  • Do brainwaves (EEGs) in older adults with hearing loss change after using hearing devices?
  • Are there differences in how social older adults with hearing loss are compared to older adults without hearing loss? What Participants Will Do:
  • Participants will take questionnaires for around 60 minutes. Questionnaires will ask participants about their background, health, hearing, and how social they are. Another set of questionnaires will check their thinking ability or cognition.
  • Participants will wear an audio sensor (TILES Audio Recorder on Jelly Mobile phone) for 2 weeks. The sensor will collect and store information about a participant's voice during conversations. Once the device has information about a participant's voice such as pitch and tone it will store this information and delete the audio recording. Words spoken during conversations will be deleted.
  • (Optional) Participants can choose to participate in a 45-60-minute EEG (electroencephalogram) recording session. Participants will have sensors placed on top of their heads. Sensors will record the participants' brainwaves. Sounds will be played to see how participants' brainwaves change when they hear sounds. Eligible participants will be invited to participate in 4-month follow-up study.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
51mo left

Started Jan 2026

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress8%
Jan 2026Jun 2030

First Submitted

Initial submission to the registry

January 8, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 17, 2025

Completed
12 months until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2027

Expected
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2030

Last Updated

January 13, 2026

Status Verified

January 1, 2026

Enrollment Period

1.5 years

First QC Date

January 8, 2025

Last Update Submit

January 11, 2026

Conditions

Keywords

hearing losshearing aidscognitiondementia

Outcome Measures

Primary Outcomes (1)

  • Cognitive test- MoCA

    MoCA (MoCA-Basic if appropriate) score

    Baseline and 4-month after hearing aid use

Secondary Outcomes (5)

  • Cognitive Test- Digit Span Test

    Baseline, 4-month after hearing aid use

  • Audio sensor- speech arousal

    Baseline, 4-month after hearing aid use

  • Audio sensor- speech activity

    Baseline and 4-month after hearing aid use

  • EEG Measures

    Baseline, 4-month after hearing aid use

  • Auditory oddball task

    Baseline and 4-mo after hearing aid use

Study Arms (3)

Adults with bilateral hearing loss (hearing aid users)

Participants with bilateral hearing loss (defined as those with speech-frequency pure-tone average \>=25 dB HL bilaterally) and currently using hearing aids.

Device: Hearing aid use

Adults without hearing loss

Hearing loss defined as speech-frequency pure-tone average \>=25 dB HL bilaterally

Adults with hearing loss (non-hearing aid users)

Participants with bilateral hearing loss (defined as those with speech-frequency pure-tone average \>=25 dB HL bilaterally) and not currently using hearing aids.

Interventions

Hearing aid use will be discussed with all eligible participants with hearing loss and will be encouraged to pursue hearing aid fitting through standard clinical indications via participants' insurance and audiologists.

Adults with bilateral hearing loss (hearing aid users)

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals meeting the inclusion criteria will be recruited from the affiliated tertiary hospitals and hearing aid centers. Both individuals with audiometry-measured bilateral hearing loss who are clinically indicated for hearing aid fitting and healthy volunteers without hearing loss will be recruited to participant in the study.

You may qualify if:

  • Age \>= 60 years
  • English or Spanish speaking
  • Group 1- older adults with normal hearing defined as speech frequency PTA \<25dB HL in bilateral ears
  • Group 2- older adults with bilateral hearing loss who are not using hearing aids
  • Group 3- older adults with bilateral hearing loss, who are currently using hearing aids

You may not qualify if:

  • Age \<60 years
  • Unable to complete questionnaires in English or Spanish

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Los Angeles General Medical Center

Los Angeles, California, 90033, United States

RECRUITING

University of Southern California

Los Angeles, California, 90066, United States

RECRUITING

MeSH Terms

Conditions

Hearing LossDementia

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsBrain DiseasesCentral Nervous System DiseasesNeurocognitive DisordersMental Disorders

Central Study Contacts

Janet Choi, MD, MPH

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

January 8, 2025

First Posted

January 17, 2025

Study Start

January 1, 2026

Primary Completion (Estimated)

June 30, 2027

Study Completion (Estimated)

June 30, 2030

Last Updated

January 13, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations