Posterior Wall Sparing of Laparoscopic Cholecystectomy in Cirrhotic Patients

NCT06778928 | Not Yet Recruiting DMC

• 1 other identifier: cholecystectomy cirrhotic
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

To assess the outcome of posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients in Assuit university hospitals and El Rajhi hospital.

Conditions

Cholecystitis in Cirrhotic Patients

Outcome Measures

Primary Outcomes (5)

• Intra and Post-operative haemorrhage

  Surgery then 2 days follow up

• Postoperative bile leak

  Surgery then 1 week follow up

• Changes of liver function tests

  AST, ALT, Billirubin

  Surgery then 1 week follow up

• Worsening of ascites

  Surgery then 1 week follow up

• Port site infection

  Surgery then 1 week folow up

Secondary Outcomes (2)

• Operative time

  From the end of induction of anasthesia to the closure of port site incisions

• Postoperative hospital stay

  surgery then up to 1 week hospital stay before discharge

Study Arms (1)

Posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients

To assess the outcome of posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patient

Procedure: laparoscopic cholecystectomy

Interventions

laparoscopic cholecystectomy PROCEDURE

Posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients

Posterior wall sparing of laparoscopic cholecystectomy in cirrhotic patients

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

60 cirrhotic patients age from 18 to 60 years who were admitted for cholecystectomy

You may qualify if:

• Patient age 18 - 60 years old Child A and B cirrhotic patients with Cholelithiasis Patient fit for surgery

You may not qualify if:

• Patient with pervious abdominal surgery

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Shaikh AR, Muneer A. Laparoscopic cholecystectomy in cirrhotic patients. JSLS. 2009 Oct-Dec;13(4):592-6. doi: 10.4293/108680809X12589999537959.

  PMID: 20202403 BACKGROUND

• Schiff J, Misra M, Rendon G, Rothschild J, Schwaitzberg S. Laparoscopic cholecystectomy in cirrhotic patients. Surg Endosc. 2005 Sep;19(9):1278-81. doi: 10.1007/s00464-004-8823-z. Epub 2005 Jul 21.

  PMID: 16021366 BACKGROUND

• Palanivelu C, Rajan PS, Jani K, Shetty AR, Sendhilkumar K, Senthilnathan P, Parthasarthi R. Laparoscopic cholecystectomy in cirrhotic patients: the role of subtotal cholecystectomy and its variants. J Am Coll Surg. 2006 Aug;203(2):145-51. doi: 10.1016/j.jamcollsurg.2006.04.019. Epub 2006 Jun 22.

  PMID: 16864026 BACKGROUND

• Cassinotti E, Baldari L, Boni L, Uranues S, Fingerhut A. Laparoscopic Cholecystectomy in the Cirrhotic: Review of Literature on Indications and Technique. Chirurgia (Bucur). 2020 Mar-Apr;115(2):208-212. doi: 10.21614/chirurgia.115.2.208.

  PMID: 32369724 BACKGROUND

MeSH Terms

Interventions

Cholecystectomy, Laparoscopic

Intervention Hierarchy (Ancestors)

Cholecystectomy; Biliary Tract Surgical Procedures; Digestive System Surgical Procedures; Surgical Procedures, Operative; Laparoscopy; Endoscopy; Minimally Invasive Surgical Procedures

Central Study Contacts

Adnan mohamed Mohamed Mohamed salem

CONTACT

01111846484; Adnan.16281240@med.aun.edu.eg

Mostafa Mahmoud Mohamed Ibrahim, Lecturer

CONTACT

01095295794; mostafamahmoud562@au.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: October 11, 2024
• First Posted: January 16, 2025
• Study Start: January 1, 2025
• Primary Completion: April 1, 2026
• Study Completion: April 1, 2026
• Last Updated: January 16, 2025

Record last verified: 2024-10