Effect of Environment on the Central and Peripheral Nervous System

NCT06778356 | Enrolling By Invitation

• 1 other identifier: STUDY007343
• Study Type: interventional
• Target: 95
• Locations: 1 country
• Sites: 1

Brief Summary

The main goal of this study is to understand how different environments influence both mental responses, like overthinking (rumination), and physical reactions, such as heart rate and blood pressure, after a challenging task.

Conditions

Rumination

Keywords

Rumination, nature exposure, respiratory sinus arrhythmia, blood pressure

Outcome Measures

Primary Outcomes (3)

• Respiratory Sinus Arrhythmia (RSA)

  Respiratory sinus arrhythmia will be measured during a baseline (20 minutes), challenging task (19 minutes) and the recovery period (10 minutes).

• Blood pressure

  Systolic (SBP) and diastolic blood pressure (DBP) will be measured during a baseline (20 minutes), challenging task (19 minutes), and recovery period (10 minutes).

• Remote Associates Test (RAT)

  In this study, the remote associates test (RAT) will be used as a challenging task to induce sympathetic arousal. Each RAT item consists of three words, participants will be asked to generate a fourth word/solution associated with the words presented by means of a compound word, synonymy, or semantic association. The participant has provided a fourth/solution word or the 30 second time limit. The task will consist of a total of 39 trials, including 5 practice trials.

  Participants will complete the RAT task for 19 minutes (44 trials).

Study Arms (2)

Built environment assignment

EXPERIMENTAL

Participants will complete the study session in a built environment

Other: Built environment

Natural environment

EXPERIMENTAL

Participants will complete the study session in a natural environment.

Other: Natural environment

Interventions

Built environment OTHER

Participants will complete the study session at a University student center.

Built environment assignment

Natural environment OTHER

Participants will complete the study session in a nature trail.

Natural environment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals 18 years of age or older.

You may not qualify if:

• Individuals with a history of cardiovascular disease or disorders, those who are pregnant, or are taking medications which may alter/affect cardiovascular function.

Sponsors & Collaborators

• University of South Florida: lead

Study Sites (1)

University of South Florida

Tampa, Florida, 33620, United States

Location

MeSH Terms

Conditions

Rumination Syndrome; Arrhythmia, Sinus

Interventions

Built Environment

Condition Hierarchy (Ancestors)

Gastrointestinal Diseases; Digestive System Diseases; Feeding and Eating Disorders; Mental Disorders; Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Environment Design; Environment; Environment and Public Health

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD student

Study Record Dates

• First Submitted: January 10, 2025
• First Posted: January 16, 2025
• Study Start: February 14, 2025
• Primary Completion (Estimated): May 20, 2026
• Study Completion (Estimated): May 20, 2026
• Last Updated: March 25, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)