Stretching and Diabetes

NCT06774105 | Completed

• 1 other identifier: 260-2024
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

Diabetes mellitus is a persistent disease characterized by alterations in glucose metabolism due to insufficient insulin production or decreased sensitivity to insulin. Exercise is the most effective non-pharmacological intervention to manage glucose levels and improve insulin sensitivity in people with diabetes. However, little is known regarding the potential effects of stretching. The objective of this study was to understand if six weeks of whole body static stretching could be adopted to manage glycemia and improve insulin sensitivity in a sample of active people with type 1 diabetes.

Conditions

Type 1 Diabetes (T1D)

Keywords

Type 1 diabetes; stretching; insulin sensitivity; insulin requirements; blood glucose

Outcome Measures

Primary Outcomes (1)

• Blood Glucose

  From enrollment to the end of treatment at 6 weeks

Secondary Outcomes (2)

• Insulin Requirements

  From enrollment to the end of treatment at 6 weeks

• Insulin Sensitivity

  From enrollment to the end of treatment at 6 weeks

Study Arms (2)

CC

NO INTERVENTION

The participants continue with their own activities for the study period

SS

EXPERIMENTAL

The participants undergo a static stretching protocol twice a week for six weeks. The protocol consists in 2 sessions per week, each comprising 8 exercises targeting all major muscle groups: 1) Hamstrings, 2) Knee Extensors, 3) Dorsal muscles, 4) Pectoralis muscles, 5) Elbow Flexors (biceps), 6) Elbow Extensors (triceps), 7) Adductors, and one day 8a) Spine Extensors while the second 8b) Spine Flexors. Each exercise involved 4 sets of 30 seconds of SS and 30 seconds of rest.

Other: Static Stretching

Interventions

Static Stretching OTHER

The protocol consisted in 2 sessions per week, each comprising 8 exercises of static stretching targeting all major muscle groups: 1) Hamstrings, 2) Knee Extensors, 3) Dorsal muscles, 4) Pectoralis muscles, 5) Elbow Flexors (biceps), 6) Elbow Extensors (triceps), 7) Adductors, and one day 8a) Spine Extensors while the second 8b) Spine Flexors. Each exercise involved 4 sets of 30 seconds of SS and 30 seconds of rest.

SS

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• have a diagnosis of type 1 diabetes from at least 1 year
• exercise regularly 2 to 3 times per week
• perform exercise activities other than stretching
• absence of other diabetes-related diseases or comorbidities that prevent them from safely exercising
• HbA1c level ≤ 7%
• BMI ≤ 29.9 kg/m²
• use a CGM reader to monitor glucose levels and daily CHO intake (g) and insulin administration (IU/die).

You may not qualify if:

• have a diagnosis of type 1 diabetes from less than 1 year
• exercise less or more than 2 to 3 times per week
• perform stretching exercises during the study period
• presence of other diabetes-related diseases or comorbidities that prevent them from safely exercising
• HbA1c level greater than 7%
• BMI greater than 29.9 kg/m²
• not using a CGM reader to monitor glucose levels and daily CHO intake (g) and insulin administration (IU/die).

Sponsors & Collaborators

• University of Palermo: lead

Study Sites (1)

University of Palermo

Palermo, IT, 90133, Italy

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1; Insulin Resistance

Interventions

Muscle Stretching Exercises

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Autoimmune Diseases; Immune System Diseases; Hyperinsulinism

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: January 8, 2025
• First Posted: January 14, 2025
• Study Start: June 1, 2024
• Primary Completion: November 30, 2024
• Study Completion: November 30, 2024
• Last Updated: January 14, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)