Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone

NCT06773104 | Completed DMC

• 1 other identifier: diab123
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

24 patienta with non restorable anterior teeth underwent extraction with immediate implant installation using bone grafts either autogenous tooth bone graft or allogenic bone graft Autogenous tooth bone graft group (study group): 12 patients will have immediate implant placement with autogenous tooth bone graft. • Allogeneic bone graft group (control group): 12 patients will have immediate implant placement with allogeneic bone graft (demineralized freeze dried bone allograft - cortico cancellous).

Conditions

Immediate Dental Implants; Thin Labial Plate of Bone Pre-extraction; Hopeless Tooth in Esthetic Zone

Keywords

autogenous tooth bone graft; allogenic bone graft; grafting the jumbing gap; immediate dental implant

Outcome Measures

Primary Outcomes (2)

• labial bone thickness

  measuring thickness of labial bone labial to the implant

  6 months

• marginal bone loss

  6 months

Secondary Outcomes (3)

• bone density around dental implant

  6 months

• implant secondary stability

  6 months

• implant success

  6 months

Study Arms (2)

Autogenous tooth bone graft group

EXPERIMENTAL

Twelve patients receiving immediate implant placement with autogenous fresh partially demineralized dentin graft.

Procedure: Allogeneic bone graft with immediate implant placement

Allogeneic bone graft group (control group)

ACTIVE COMPARATOR

Patients receiving immediate dental implant placement with allogeneic bone graft (DFDBA) for grafting of the jumping gap.

Procedure: immediate implant with allogenic bone graft

Interventions

immediate implant with allogenic bone graft PROCEDURE

after atraumatic extraction immediate implant will be inserted with allogenic bone graft

Allogeneic bone graft group (control group)

Allogeneic bone graft with immediate implant placement PROCEDURE

Immediate dental implant placement with grafting of the jumping gap using allogeneic bone graft (DFDBA).

Autogenous tooth bone graft group

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients with non restorable maxillary anterior teeth need to be extracted.
• Thin labial plate of bone of the tooth to be extracted.
• Patients age above 20years old.
• Good oral hygiene.
• No signs of acute infection or inflammation

You may not qualify if:

• Prior radiation therapy.
• Soft and hard tissue pathology at the operation site.
• Any relevant systemic disease or medication that might compromise bone healing.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Faculty of Dentistry

Tanta, 3111, Egypt

Location

Study Officials

• diab abdelgaied diab, master

  faculty of dentistry tanta university

  PRINCIPAL INVESTIGATOR

• Rafic ramadan bedir, professor

  faculty of dentistry tanta university

  PRINCIPAL INVESTIGATOR

• Ibrahim mohammed nowair, professor

  faculty of dentistry tanta university

  PRINCIPAL INVESTIGATOR

• Mona samy sheta, lecturer

  faculty of dentistry tanta university

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Model Details: non restorable anterior teeth with thin labial plate of bone

Study Record Dates

• First Submitted: December 30, 2024
• First Posted: January 14, 2025
• Study Start: March 25, 2024
• Primary Completion: October 16, 2025
• Study Completion: October 16, 2025
• Last Updated: January 20, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)