Radiodiagnostic Properties of Maxillary Antroliths

NCT06765148 | Completed

• 1 other identifier: 2024/299
• Study Type: observational
• Target: 1,200
• Locations: 1 country
• Sites: 1

Brief Summary

Background: To evaluate the frequency and radiodiagnostic characteristics of maxillary antroliths using cone beam computed tomography. Materials and Methods: A review of 1166 patients aged 11-85 years was conducted to assess the frequency of maxillary antroliths, considering sex, age, and location. The relationship between antroliths and sex, location, dental treatment status, and sinus inflammation was evaluated. The shape, size, and volume of the antroliths were also analyzed. Significance was set at p=0.05 for statistical analysis.

Conditions

Antrolith; Maxillary Sinus

Keywords

cone beam computed tomography; Lithiasis; maxillary sinus; panoramic radiography

Outcome Measures

Primary Outcomes (5)

• Antrolith descriptive analysis

  CBCT images were examined in axial, sagittal, and coronal slices to investigate the presence of antroliths. The age and sex information of the detected cases were recorded.

  for three days from the beginning of the study

• Antrolith localization and relationship the dental status evaluation

  Each sinus cavity exhibiting antroliths was evaluated for distribution and location as follows: (1) unilateral or bilateral, (2) single or multiple, (3) tooth extraction/root canal treatment/residual root fragment/implant/periodontal disease and/or periapical lesion (any dental cause of sinus inflammation), (4) premolar or molar region, and (5) sinus floor, lateral wall, or medial wall.

  for three days from the beginning of the study

• Antrolith and mucosal thickness classification

  the detected antroliths were categorized according to the classification of Cho et al. In this classification made according to the sizes of antroliths, Punctate = ≤3 mm in both height and width, Linear = ≤3 mm and more than treble in width, and Amorphous = \>3 mm in both width and height. Additionally, the locations of the openings of the maxillary sinus ostiums were evaluated, and mucosal thickening, if any, was measured. Mucosal thickness measurements were made on coronal slices using NewTom's NNT viewer measuring tool. Similar to Chen et al., the sinus membrane thickness was measured perpendicular to the bone wall, from the maximum thickest region. Similar to Chen et al.'s classification of sinus membrane thickness measurements, which used Block and Dostoury's classification, the mucosal thickness was classified into three subgroups: membrane thicknesses \<2 mm, 2-5 mm, and \>5 mm. Also, similar to the article by Cho et al., the degree of inflammation in the maxillary sinus was

  for three days from the beginning of the study

• Antrolith volume measurement

  3D reconstruction and volume measurements of antroliths were performed using the ITK SNAP software (free software under the GNU General Public License developed by the National Institutes of Health, the US National Institute of Biomedical Imaging and Bioenergy needs, the US National Library of Medicine, the Universities of Pennsylvania and North Carolina, and an independent group of developers).

  for three days from the beginning of the study

• Different images evaluation for antrolit

  In addition, the visibility of antroliths detected on CBCT was also evaluated using panoramic radiographs taken from the patient (Fig 2). The detectability of antroliths in DPRs was evaluated by observers as detectable, suspicious, and undetectable.

  for three days from the beginning of the study

Interventions

Retrospective radiologic study OTHER

Retrospective radiologic study

Eligibility Criteria

• Age: 11 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Retrospective maxillary sinus included CBCT images

You may qualify if:

• DPR and CBCT and also had a maximum of 3 months
• Image quality was sufficient
• No artifacts CBCT images

You may not qualify if:

• Tomographic images that contained pathologies such as cysts/tumors in the
• Insufficient diagnostic quality
• History of maxillofacial trauma or surgery, any syndrome/bone-related disease/metabolic disease
• Insufficient diagnostic quality or patient position-related artifacts

Sponsors & Collaborators

• Recep Tayyip Erdogan University Training and Research Hospital: lead

Study Sites (1)

Recep Tayyip Erdogan University Training and Research Hospital

Rize, 53100, Turkey (Türkiye)

Location

Related Publications (1)

• Gunacar DN, Kose TE, Ceren F. Radiodiagnostic properties of maxillary antroliths: a retrospective cone beam computed tomography study. BMC Oral Health. 2025 Feb 19;25(1):259. doi: 10.1186/s12903-025-05641-y.

  PMID: 39972501 DERIVED

MeSH Terms

Conditions

Lithiasis

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof.

Study Record Dates

• First Submitted: December 24, 2024
• First Posted: January 9, 2025
• Study Start: December 1, 2024
• Primary Completion: December 22, 2024
• Study Completion: December 23, 2024
• Last Updated: January 9, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)