Socket Seal Surgery
Laser Assisted Socket Seal Surgery Using Bioactive Glass for Dental Implant Site Development
1 other identifier
interventional
45
1 country
1
Brief Summary
laser photo biomodulation (PBM) as a supplement to socket seal surgery
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Nov 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 10, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 10, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
February 10, 2024
CompletedFirst Submitted
Initial submission to the registry
January 3, 2025
CompletedFirst Posted
Study publicly available on registry
January 8, 2025
CompletedJanuary 8, 2025
November 1, 2022
1 year
January 3, 2025
January 3, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
alveolar ridge dimensional changes in height and width measures
at base line and after 9 months
Secondary Outcomes (1)
bone biopsy
after 9 months
Study Arms (3)
control group
PLACEBO COMPARATORplatelet rich fibrin membrane
test 1 group
EXPERIMENTALbioactive glass
test 2group
ACTIVE COMPARATORbioactive glass and Photobiomodulation
Interventions
supplied as resorbable form, (400-800um) particle siz
The used laser parameters were set as: wavelength, 980 nm; power, 0.55 W; energy, 36 J; power density, 0.76 W cm2
10 ml of blood was withdrawn from the patient and immediately centrifuged for 10 minutes at 3000 revolutions/min and the layer of fibrin clot was obtained
Eligibility Criteria
You may qualify if:
- Presence of at least a periodontal-affected and non-restorable tooth in posterior region (Class II sockets).
- At least 10% plaque control scoring was accepted
- A moderate to thick gingival phenotype
You may not qualify if:
- systemic diseases or conditions that may compromise healing or bone metabolism,
- having a history of radiotherapy, chemotherapy or bisphosphonate therapy, previous use of antibiotics in the last 3
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
, Faculty of Oral and Dental Medicine, Delta University for Science and Technology (DU), Dakahlia, Egypt
Dakahlia, Egypt
Related Publications (1)
Hazzaa HH, Shiekh MAME, AbdAllah MF, Abdelgawad N, El-Mahdy MA, Shoshan HS, Elewa GM. Laser-assisted socket seal surgery using bioactive glass for dental implant site development: a randomized clinical trial. Sci Rep. 2025 Dec 9;15(1):43386. doi: 10.1038/s41598-025-28824-7.
PMID: 41360883DERIVED
Related Links
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- associate professor
Study Record Dates
First Submitted
January 3, 2025
First Posted
January 8, 2025
Study Start
November 10, 2022
Primary Completion
November 10, 2023
Study Completion
February 10, 2024
Last Updated
January 8, 2025
Record last verified: 2022-11
Data Sharing
- IPD Sharing
- Will not share