NCT06759597

Brief Summary

The macula has a very high concentration of photoreceptor cells - the cells that detect light. They send signals to the brain, which interprets them as images. The rest of the retina processes our peripheral, or side vision To explore whether cataract surgery evokes development or relapse of choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) patients followed for a 1-year postoperative period

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2025

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 30, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 6, 2025

Completed
26 days until next milestone

Study Start

First participant enrolled

February 1, 2025

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2026

Completed
Last Updated

January 6, 2025

Status Verified

December 1, 2024

Enrollment Period

1 year

First QC Date

December 30, 2024

Last Update Submit

December 30, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • To figure out the possibility of Postoperative conversion or relapse ( Dry to wet , wet to reactivated CNV)

    To explore whether cataract surgery evokes development or relapse of choroidal neovascularization (CNV) in wet age-related macular degeneration (AMD) patients followed for a 1-year postoperative period

    baseline

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

old age population had phacoemulsefcation with history of neovascular AMD

You may qualify if:

  • Above 50 years old
  • not diabetic individuals
  • wet ARMD

You may not qualify if:

  • intraoperative complications
  • Eyes with diseases predisposing them for postoperative macular edema, preexisting macular edema, and eyes that developed cystoid macular edema
  • active ocular inflammation or infection \_glaucoma
  • A preoperatively worsened VA regardless phE
  • ocular trauma
  • patients with central retinal ischemia
  • previous vitrectomy
  • dry amd

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

MeSH Terms

Conditions

Macular Degeneration

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Central Study Contacts

Demiana Alkes Zakka Labib Demiana Alkes Zakka Labib

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Month
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
doctor

Study Record Dates

First Submitted

December 30, 2024

First Posted

January 6, 2025

Study Start

February 1, 2025

Primary Completion

February 1, 2026

Study Completion

April 1, 2026

Last Updated

January 6, 2025

Record last verified: 2024-12