CRP /albumin Ratio and Neutrophil Lymphocyte Ratio in Predicting Activity in IBD Patients

NCT06750315 | Not Yet Recruiting

• 1 other identifier: CRP/ALB and N/L In active IBD
• Study Type: observational
• Target: 35
• Locations: 1 country
• Sites: 2

Brief Summary

This study aimed to assess the clinical utility of the NLR (neutrophil lymphocyte ratio) and CRP Albumin ratio in predicting activity of IBD Patients in assiut university

Conditions

Inflammatory Bowel Disease (IBD)

Keywords

CRP/ALB ratio; N/L ratio

Outcome Measures

Primary Outcomes (1)

• C-reactive protein /albumin ratio and neutrophil lymphocyte ratio in predicting activity in Inflammatory Bowel Disease Patients

  Neutrophil lymphocyte ratio and CRP/Albumin ratio in detecting activity in IBD Patients.

  1 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Pt more than 18 years not DM not cardiac failure Not Liver failure No malignancy

You may qualify if:

• Patients more than 18 years newly diagnosed as IBD

You may not qualify if:

• Patients Not DM Not cardiac failure Not Liver failure No malignancy

Sponsors & Collaborators

• Assiut University: lead

Study Sites (2)

Assiut University

Asyut, Egypt

Location

Assiut university hospital

Egypt, Assiut, Egypt

Location

Related Publications (4)

• Torun S, Tunc BD, Suvak B, Yildiz H, Tas A, Sayilir A, Ozderin YO, Beyazit Y, Kayacetin E. Assessment of neutrophil-lymphocyte ratio in ulcerative colitis: a promising marker in predicting disease severity. Clin Res Hepatol Gastroenterol. 2012 Oct;36(5):491-7. doi: 10.1016/j.clinre.2012.06.004. Epub 2012 Jul 27.

  PMID: 22841412 BACKGROUND

• Nguyen AL, Brick C, Liu D, Gibson DJ, Gibson PR, Sparrow MP. Clinical utility of C-reactive protein-to-albumin ratio in the management of patients with inflammatory bowel disease. JGH Open. 2024 Apr 15;8(4):e13059. doi: 10.1002/jgh3.13059. eCollection 2024 Apr.

  PMID: 38623491 BACKGROUND

• Demir AK, Demirtas A, Kaya SU, Tastan I, Butun I, Sagcan M, Sahin S, Tasliyurt T, Yilmaz A. The relationship between the neutrophil-lymphocyte ratio and disease activity in patients with ulcerative colitis. Kaohsiung J Med Sci. 2015 Nov;31(11):585-90. doi: 10.1016/j.kjms.2015.10.001. Epub 2015 Oct 31.

  PMID: 26678939 BACKGROUND

• Langley BO, Guedry SE, Goldenberg JZ, Hanes DA, Beardsley JA, Ryan JJ. Inflammatory Bowel Disease and Neutrophil-Lymphocyte Ratio: A Systematic Scoping Review. J Clin Med. 2021 Sep 17;10(18):4219. doi: 10.3390/jcm10184219.

  PMID: 34575330 BACKGROUND

MeSH Terms

Conditions

Inflammatory Bowel Diseases

Condition Hierarchy (Ancestors)

Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases

Central Study Contacts

Amira Mohamed Ali Ahmed

CONTACT

01090176978; am3859282@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer

Study Record Dates

• First Submitted: September 20, 2024
• First Posted: December 27, 2024
• Study Start: January 1, 2025
• Primary Completion: October 1, 2025
• Study Completion: December 1, 2025
• Last Updated: December 27, 2024

Record last verified: 2024-09

Locations

EG (2)