Serum Ferritin and Prognosis of DKA

NCT06748365 | Recruiting

• 1 other identifier: Soh-Med--24-12-07MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

the aim of this study is to: evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA. Specifically, the correlation between its level and the severity of DKA at presentation and determine its prognostic value in predicting short-term outcomes.

Conditions

Diabetic Ketoacidosis

Keywords

serum Ferritin; Diabetic Ketoacidosis

Outcome Measures

Primary Outcomes (1)

• evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA. Specifically, the correlation between its level and the severity of DKA at presentation and determine its prognostic value

  Through the study completion, an average of 1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with DKA admitted to the emergency department or intensive care units of Sohag university Hospital

You may qualify if:

• All patients with DKA :
• Adult Aged 18 years old or older .
• Type 1 DM , type 2 DM
• Diagnosis of DKA based on the American Diabetes Association criteria: blood glucose \>250 mg/dL, arterial pH \<7.3, serum bicarbonate \<18 mEq/L,

You may not qualify if:

• Patients age less than 18 years old
• Iron deficiency anemia and iron overload
• Chronic Inflammatory Diseases: Conditions such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease
• Acute and chronic infections, including bacterial, viral, and fungal infections
• Pt presented with other acute complication (MI,stroke)
• CKD patients
• Patients with chronic liver diseases
• Patients with malignancy
• Pregnant women.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university Hospitals

Sohag, Sohag Governorate, 82524, Egypt

RECRUITING

MeSH Terms

Conditions

Diabetic Ketoacidosis

Condition Hierarchy (Ancestors)

Ketosis; Acidosis; Acid-Base Imbalance; Metabolic Diseases; Nutritional and Metabolic Diseases; Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases

Central Study Contacts

Joseph Medhat Sobhy, resident in internal medicine

CONTACT

+2001011041077; joeisgreatyeah@gmail.com

Marium Medhat Sobhy, resident in opthalmology

CONTACT

+2001023322977; mariummedhat3@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at internal medicine department

Study Record Dates

• First Submitted: December 18, 2024
• First Posted: December 27, 2024
• Study Start: January 1, 2025
• Primary Completion: January 1, 2026
• Study Completion: February 1, 2026
• Last Updated: May 14, 2025

Record last verified: 2024-12

Locations

EG (1)