NCT06748092

Brief Summary

Clinical validation of iCare IC1000 tonometer per ANSI Z80.10:2014 standard

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
250

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 19, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 27, 2024

Completed
10 months until next milestone

Study Start

First participant enrolled

October 21, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2026

Completed
Last Updated

December 26, 2025

Status Verified

December 1, 2025

Enrollment Period

4 months

First QC Date

December 19, 2024

Last Update Submit

December 19, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Demonstrate compliance with ANSI Z80.10:2014-Ophthalmics-Ophthalmic Instruments-Tonometers

    Subjects will be distributed into Low IOP, Medium IOP, and High IOP groups based on the reference tonometer measurements. The iCare IC1000 Tonometer measurements shall be within +/-5.0 mmHg of the reference tonometer measurements in all groups.

    Through study completion, an average of 6 months

Secondary Outcomes (1)

  • Retrospective analysis of "Quick Measure" mode

    Through study completion, an average of 6 months

Study Arms (1)

iCare IC1000 vs GAT, iCare IC200 and Perkins

EXPERIMENTAL
Device: iCare IC1000Device: iCare IC200Device: GATDevice: Perkins

Interventions

Measurement of Intraocular Pressure (IOP) in sitting and supine position

iCare IC1000 vs GAT, iCare IC200 and Perkins

Measurement of Intraocular Pressure (IOP) in sitting and supine position

iCare IC1000 vs GAT, iCare IC200 and Perkins
GATDEVICE

Measurement of Intraocular Pressure (IOP) in sitting position

iCare IC1000 vs GAT, iCare IC200 and Perkins
PerkinsDEVICE

Measurement of Intraocular Pressure (IOP) in supine position

iCare IC1000 vs GAT, iCare IC200 and Perkins

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 18 years

You may not qualify if:

  • Subjects with only one functional eye
  • Subjects having poor or eccentric fixation in the study eye
  • High corneal astigmatism \>3D in the study eye
  • Central corneal scarring
  • History of prior incisional glaucoma surgery or corneal surgery, including corneal refractive laser surgery in the study eye
  • Microphthalmos
  • Buphthalmos
  • Contact lens use within one week of continuous wear and within one hour if lens is worn occasionally
  • Dry eyes (clinically significant)
  • Lid squeezers - blepharospasm
  • Nystagmus
  • Keratoconus
  • Any other corneal or conjunctival pathology or infection relevant to this study
  • Central corneal thickness greater than 600 µm or less than 500 µm in the study eye
  • Cataract Extraction within last 2 months in the study eye

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nova Scotia Health/Dalhousie University

Halifax, Nova Scotia, B3H 2Y9, Canada

RECRUITING

Central Study Contacts

Balwantray Chauhan, Prof.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
Investigator cannot see the measurement results.
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 19, 2024

First Posted

December 27, 2024

Study Start

October 21, 2025

Primary Completion

February 28, 2026

Study Completion

February 28, 2026

Last Updated

December 26, 2025

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations