NCT06744985

Brief Summary

The goal of this prospective cohort study is to compare the predictive accuracy of the Revised Trauma Score (RTS) and the MGAP score in determining clinical outcomes among multiple trauma patients hospitalized at a trauma center in Iraq. The main questions it aims to answer are: Which score, RTS or MGAP, provides a more accurate prediction of clinical outcomes, including mortality? Are there specific subgroups of trauma patients where one scoring system outperforms the other? Participants will: Be assessed using both the RTS and MGAP scores upon admission. Have their clinical outcomes, including mortality and other relevant indicators, monitored throughout their hospital stay.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
7mo left

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress68%
Jan 2025Dec 2026

First Submitted

Initial submission to the registry

December 12, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 20, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

January 20, 2025

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 10, 2026

Expected
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 20, 2026

Last Updated

March 4, 2026

Status Verified

March 1, 2026

Enrollment Period

1.9 years

First QC Date

December 12, 2024

Last Update Submit

March 3, 2026

Conditions

Multiple Trauma/Injuries

Keywords

RTSMGAP

Outcome Measures

Primary Outcomes (3)

  • In hospital mortality

    Mortality (death) during hospitalization.

    In-Hospital Phase (average of 7 days through discharge)

  • Accuracy Assessment of the Revised Trauma Score (RTS)

    The total RTS score ranges from 0 to approximately 12, with lower scores indicating more severe injuries and a higher risk of mortality.

    the first 6 hours after ER admission

  • Accuracy Assessment of the MGAP score

    (mechanism, Glasgow coma scale, age, and blood pressure), Total scores can range from 3 to 29, with a higher score predicting a better prognosis.

    the first 6 hours after ER admission

Secondary Outcomes (3)

  • Length of Hospitalization

    Up to discharge, an average of 7 days

  • Number of Participants Requiring ICU Admission

    Up to discharge, an average of 7 days

  • Number of Participants Requiring Surgical Intervention

    Up to discharge, an average of 7 days

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Multiple trauma patients were admitted to the trauma and emergency department at Al-Kadhimiya Teaching Hospital in Baghdad.

You may qualify if:

  • Presentation to the trauma center within 6 hours of injury.
  • Availability of complete clinical and demographic data for scoring using RTS and MGAP.
  • Patients who consent to participate in the study or whose legal representatives provide consent.
  • Capability to assess outcomes such as survival, ICU admission, and complications.

You may not qualify if:

  • Patients who expired before scoring or evaluation
  • Missing or unreliable medical data for RTS or MGAP score calculations.
  • Transfers from other facilities with interventions that could impact RTS or MGAP reliability.
  • Pregnant patients, due to the unique considerations of trauma in pregnancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, Iraq

RECRUITING

Related Publications (10)

  • Kelly JF, Ritenour AE, McLaughlin DF, Bagg KA, Apodaca AN, Mallak CT, Pearse L, Lawnick MM, Champion HR, Wade CE, Holcomb JB. Injury severity and causes of death from Operation Iraqi Freedom and Operation Enduring Freedom: 2003-2004 versus 2006. J Trauma. 2008 Feb;64(2 Suppl):S21-6; discussion S26-7. doi: 10.1097/TA.0b013e318160b9fb.

    PMID: 18376168BACKGROUND

  • Heydari Farhad. The effects of multidisciplinary education for nurses and physicians on the management of patients with multiple trauma.

    BACKGROUND

  • Heydari F, Maghami MH, Esmailian M, Zamani M. The Effect of Implementation of the Standard Clinical Practice Guideline (CPG) for Management of Multiple Trauma Patients Admitted to an Emergency Department. Adv J Emerg Med. 2017 Dec 11;2(1):e5. doi: 10.22114/AJEM.v0i0.37. eCollection 2018 Winter.

    PMID: 31172068BACKGROUND

  • Sartorius D, Le Manach Y, David JS, Rancurel E, Smail N, Thicoipe M, Wiel E, Ricard-Hibon A, Berthier F, Gueugniaud PY, Riou B. Mechanism, glasgow coma scale, age, and arterial pressure (MGAP): a new simple prehospital triage score to predict mortality in trauma patients. Crit Care Med. 2010 Mar;38(3):831-7. doi: 10.1097/CCM.0b013e3181cc4a67.

    PMID: 20068467RESULT

  • Javali RH, Krishnamoorthy, Patil A, Srinivasarangan M, Suraj, Sriharsha. Comparison of Injury Severity Score, New Injury Severity Score, Revised Trauma Score and Trauma and Injury Severity Score for Mortality Prediction in Elderly Trauma Patients. Indian J Crit Care Med. 2019 Feb;23(2):73-77. doi: 10.5005/jp-journals-10071-23120.

    PMID: 31086450RESULT

  • Domingues CA, Coimbra R, Poggetti RS, Nogueira LS, de Sousa RMC. New Trauma and Injury Severity Score (TRISS) adjustments for survival prediction. World J Emerg Surg. 2018 Mar 6;13:12. doi: 10.1186/s13017-018-0171-8. eCollection 2018.

    PMID: 29541155RESULT

  • Soni KD, Mahindrakar S, Gupta A, Kumar S, Sagar S, Jhakal A. Comparison of ISS, NISS, and RTS score as predictor of mortality in pediatric fall. Burns Trauma. 2017 Aug 8;5:25. doi: 10.1186/s41038-017-0087-7. eCollection 2017.

    PMID: 28795055RESULT

  • Roy N, Gerdin M, Schneider E, Kizhakke Veetil DK, Khajanchi M, Kumar V, Saha ML, Dharap S, Gupta A, Tomson G, von Schreeb J. Validation of international trauma scoring systems in urban trauma centres in India. Injury. 2016 Nov;47(11):2459-2464. doi: 10.1016/j.injury.2016.09.027. Epub 2016 Sep 20.

    PMID: 27667119RESULT

  • Baghi I, Shokrgozar L, Herfatkar MR, Nezhad Ehsan K, Mohtasham Amiri Z. Mechanism of Injury, Glasgow Coma Scale, Age, and Systolic Blood Pressure: A New Trauma Scoring System to Predict Mortality in Trauma Patients. Trauma Mon. 2015 Aug;20(3):e24473. doi: 10.5812/traumamon.24473. Epub 2015 Aug 1.

    PMID: 26543842RESULT

  • Farzan N, Foroghi Ghomi SY, Mohammadi AR. A retrospective study on evaluating GAP, MGAP, RTS and ISS trauma scoring system for the prediction of mortality among multiple trauma patients. Ann Med Surg (Lond). 2022 Mar 28;76:103536. doi: 10.1016/j.amsu.2022.103536. eCollection 2022 Apr.

    PMID: 35495411RESULT

MeSH Terms

Conditions

Multiple TraumaWounds and Injuries

Study Officials

  • Bashar A Abdulhassan, Assistant professor of surgery

    College Of Medicine - Nahrain University

    STUDY DIRECTOR

Central Study Contacts

Abdulillah R. Khamees

CONTACT

+9647838571013allaabed987@ced.nahrainuniv.edu.iq

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 12, 2024

First Posted

December 20, 2024

Study Start

January 20, 2025

Primary Completion (Estimated)

December 10, 2026

Study Completion (Estimated)

December 20, 2026

Last Updated

March 4, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

IR(1)