Estimating VO2 Max and Recovery

NCT06744582 | Completed

• 1 other identifier: ORI/VO2/24
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 2

Brief Summary

The study aims to estimate VO2 max levels at pre- and post-operative timepoints before and after hip arthroplasty surgery, using non-exercise-based measurement methods.

Conditions

Hip Osteoarthritis

Keywords

Osteoarthritis; Hip arthroplasty; Hip replacement; Musculoskeletal; VO2 max; Cardiovascular fitness

Outcome Measures

Primary Outcomes (1)

• Natural variation in VO2 max

  VO2 max will be estimated using seismocardiography prior to surgery, on day 1, and at 3 weeks, 6 weeks, and 12 weeks following surgery.

  From enrollment to 12 weeks after surgery

Secondary Outcomes (5)

• Patient Reported Outcome Measure (PROM) - The Hip Disability and Osteoarthritis Outcome Score (HOOS)

  From enrollment to 12 weeks after surgery

• Functional Assessment - 30 Second Chair Stand Test

  From enrollment to 12 weeks after surgery

• Functional Assessment - 40 Metre Fast-Paced Walk Test

  From enrollment to 12 weeks after surgery

• Functional Assessment - Stair Climb Test

  From enrollment to 12 weeks after surgery

• Monitoring of physical activity

  From enrollment to 12 weeks after surgery

Interventions

VO2 max OTHER

The aim of this study is to generate data on the estimation of natural variation in VO2 max changes before and after surgery using seismocardiography.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing Robot Assisted Total Hip Replacement at the Nuffield Health

You may qualify if:

• Male and female ≥ 18 years;
• Undergoing total hip replacement at Nuffield Hospital;
• Voluntary written Informed Consent obtained;
• Participant able to complete study follow-up.

You may not qualify if:

• Requiring revision hip arthroplasty;
• Patients with implanted electronic equipment, such as a pacemaker;
• Women judged by the Investigator to be of childbearing potential who are pregnant, nursing, or planning to become pregnant, and those who do not agree to remain on an acceptable method of birth control throughout the entire study period;
• Unable to provide informed consent (insufficient English, lives overseas, unable to return easily).

Sponsors & Collaborators

• Bournemouth University: lead
• Nuffield Health Bournemouth: collaborator

Study Sites (2)

Nuffield Health Hospital Bournemouth

Bournemouth, Dorset, BH1 1RW, United Kingdom

Location

Bournemouth University

Bournemouth, Dorset, BH12 2DR, United Kingdom

Location

MeSH Terms

Conditions

Osteoarthritis, Hip; Osteoarthritis

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Thomas W. Wainwright

  Bournemouth University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Orthopaedics

Study Record Dates

• First Submitted: December 16, 2024
• First Posted: December 20, 2024
• Study Start: March 27, 2025
• Primary Completion: March 25, 2026
• Study Completion: March 25, 2026
• Last Updated: April 22, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

GB (2)