The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients

NCT06742580 | Recruiting

• 1 other identifier: AFSÜ-KBB-MA-01
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 3

Brief Summary

In the etıology of Idıopathıc Acute Perıpheral Facıal Palsy, known as bell palsy, many causes have been descrıbed, such as specıfıc ımmune, ıchemıc, ınfectıous and heredıal factors. ın our study, we have observed the blood homocysteıne level that causes thrombotıc dısorders ın paralysıs patıents.

Conditions

Facial Paralysis, Peripheral; Bell Palsy

Keywords

Acute Peripheral Facial Paralysis; Homocysteine; Bell Palsy

Outcome Measures

Primary Outcomes (1)

• Homosystein test results

  The results have not been obtained from lab yet. So none results were measured .

  up to 24 weeks

Study Arms (2)

Bell palsy patient group

Patients who applied to our hospital due to idiopathic facial paralysis within the first month

control group

Healthy individuals with no known health problems

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

AFYON HEALTH SCIENCES UNIVERSITY HOSPITAL

You may qualify if:

• \- Patients admitted with acute facial paralysis

You may not qualify if:

• Facial and ear trauma or tumor
• İatrogenic
• Cholesteatoma
• Facial paralysis due to central nervous system diseases

Sponsors & Collaborators

• Murat Akın: lead

Study Sites (3)

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

ACTIVE NOT RECRUITING

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

RECRUITING

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

RECRUITING

Related Publications (4)

• Singh A, Deshmukh P. Bell's Palsy: A Review. Cureus. 2022 Oct 11;14(10):e30186. doi: 10.7759/cureus.30186. eCollection 2022 Oct.

  PMID: 36397921 BACKGROUND

• Son P, Lewis L. Hyperhomocysteinemia. 2022 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK554408/

  PMID: 32119295 BACKGROUND

• Niu X, Chen Y, Zhong Y, Xiao X. The relationship between serum homocysteine levels and sudden sensorineural hearing loss: a meta-analysis. Eur Arch Otorhinolaryngol. 2023 May;280(5):2091-2097. doi: 10.1007/s00405-023-07829-w. Epub 2023 Jan 19.

  PMID: 36658368 BACKGROUND

• Eviston TJ, Croxson GR, Kennedy PG, Hadlock T, Krishnan AV. Bell's palsy: aetiology, clinical features and multidisciplinary care. J Neurol Neurosurg Psychiatry. 2015 Dec;86(12):1356-61. doi: 10.1136/jnnp-2014-309563. Epub 2015 Apr 9.

  PMID: 25857657 BACKGROUND

MeSH Terms

Conditions

Facial Paralysis; Bell Palsy

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Herpesviridae Infections; DNA Virus Infections; Virus Diseases; Infections; Facial Nerve Diseases; Cranial Nerve Diseases

Study Officials

• Orhan Kemal KAHVECİ, PROFESSOR

  AFYON HEALTH SCIENCES UNIVERSITY HOSPITAL

  PRINCIPAL INVESTIGATOR

Central Study Contacts

MURAT AKIN, ASSISTANT DOCTOR

CONTACT

+90 272 246 33 35; makin.md279@gmail.com

Orhan Kemal KAHVECİ, PROFESSOR

CONTACT

+90 272 246 33 35; orhangs75@hotmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: assistant doctor

Study Record Dates

• First Submitted: December 13, 2024
• First Posted: December 19, 2024
• Study Start: December 1, 2023
• Primary Completion: April 1, 2025
• Study Completion: August 4, 2025
• Last Updated: December 19, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (3)