NCT06735365

Brief Summary

We divided patients in 2 groups. First group was the patients who received Oxiris filters during CRRT. Second group was the patiens who have received CRRT filters other than Oxiris. We compared the lab parameters (Urea, Creatinin, Lactate, ABG parameters and SOFA escore with together.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
426

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 23, 2024

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

December 11, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 16, 2024

Completed
Last Updated

December 31, 2024

Status Verified

December 1, 2024

Enrollment Period

5 months

First QC Date

December 11, 2024

Last Update Submit

December 26, 2024

Conditions

Sepsis - to Reduce Mortality in the Intensive Care UnitHemodiafiltrationCytokine

Outcome Measures

Primary Outcomes (1)

  • SOFA Score

    We compared SOFA scores of patients on admission and on 5th day.

    6 month

Secondary Outcomes (1)

  • Survival comparison

    6 month

Study Arms (2)

Oxiris

The group which we used oxiris filter for CRRT.

Other: CRRT

Non-Oxiris

The group which we used other filters like M150 for CRRT.

Other: CRRT

Interventions

CRRTOTHER

Hemodiafiltration

Non-OxirisOxiris

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

study population includes patients who have admission on our clinic for more than 5 days and diagnosed with sepsis who has CRRT indication

You may qualify if:

  • sepsis diagnosis CRRT indication

You may not qualify if:

  • patients under age of 18

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bakirkoy Dr Sadi Konuk Research and Training Hospital

Istanbul, Turkey (Türkiye)

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 11, 2024

First Posted

December 16, 2024

Study Start

May 23, 2024

Primary Completion

November 1, 2024

Study Completion

December 1, 2024

Last Updated

December 31, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)