Depression Among Cardiothoracic Surgery Patients in Baghdad

NCT06734169 | Not Yet Recruiting DMC

• 2 other identifiers: UNCOMIRB20241210C011
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study aims to estimate the prevalence and severity of depression among patients in the Cardiothoracic Surgery Ward in Baghdad City, Iraq, using a self-administered PHQ-9 questionnaire. The main questions it aims to answer are: What is the prevalence of depression among cardiothoracic surgery patients? How is the severity of depression distributed within this group? Are there specific environmental or demographic factors associated with higher levels of depression? Participants will: Fill out the PHQ-9 in order to measure the severity of depressive symptoms at a specific moment in time. Demographic and clinical variables such as age, gender, socioeconomic status, surgery type, comorbidities, and hospital stay length should be taken to look for a possible relationship with depression.

Conditions

Depression

Keywords

PHQ-9

Outcome Measures

Primary Outcomes (3)

• Prevalence of Depression

  Proportion of cardiothoracic surgery patients at Al-Kadhimiya Teaching Hospital who exhibit depressive symptoms.

  Data collection will occur over a 3-months period, with each participant completing the PHQ-9 assessment at a single point during this time frame.

• Severity of Depression

  The severity of depression in this study will be determined based on the scores obtained from the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 categorizes depression severity as follows: Minimal depression: Scores 0-4, indicating little to no symptoms. Mild depression: Scores 5-9, suggesting occasional symptoms that may not significantly affect daily functioning. Moderate depression: Scores 10-14, indicating more frequent symptoms that can interfere with daily life. Moderately severe depression: Scores 15-19, showing pronounced symptoms that significantly impact daily activities. Severe depression: Scores 20-27, with symptoms that are debilitating.

  Data collection will occur over a 3-months period, with each participant completing the PHQ-9 assessment at a single point during this time frame.

• Patient Health Questionnaire-9 (PHQ-9)

  The total score can range from 0 to 27. Higher scores indicate greater severity of depression.

  Data collection will occur over a 3-months period, with each participant completing the PHQ-9 assessment at a single point during this time frame.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adult patients (18 years and older) admitted to the cardiothoracic surgery ward at Al-Kadhimiya Teaching Hospital in Baghdad.

You may qualify if:

• Patients admitted to the cardiothoracic surgery ward.
• Patients who are able to understand and provide informed consent.
• Patients who have the cognitive ability to complete the PHQ-9 questionnaire.

You may not qualify if:

• Patients with a history of diagnosed psychiatric disorders other than depression.
• Patients who are critically ill or in a life-threatening condition and unable to participate.
• Patients who are unable to understand the PHQ-9 questionnaire due to language or cognitive barriers.

Sponsors & Collaborators

• Al-Nahrain University: lead

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, Iraq

Location

Related Publications (10)

• McCormick KM, Naimark BJ, Tate RB. Uncertainty, symptom distress, anxiety, and functional status in patients awaiting coronary artery bypass surgery. Heart Lung. 2006 Jan-Feb;35(1):34-45. doi: 10.1016/j.hrtlng.2005.08.002.

  PMID: 16426934 BACKGROUND

• Underwood MJ, Firmin RK, Jehu D. Aspects of psychological and social morbidity in patients awaiting coronary artery bypass grafting. Br Heart J. 1993 May;69(5):382-4. doi: 10.1136/hrt.69.5.382.

  PMID: 8518057 BACKGROUND

• Tully PJ, Baker RA. Depression, anxiety, and cardiac morbidity outcomes after coronary artery bypass surgery: a contemporary and practical review. J Geriatr Cardiol. 2012 Jun;9(2):197-208. doi: 10.3724/SP.J.1263.2011.12221.

  PMID: 22916068 BACKGROUND

• Morys JM, Bellwon J, Hofer S, Rynkiewicz A, Gruchala M. Quality of life in patients with coronary heart disease after myocardial infarction and with ischemic heart failure. Arch Med Sci. 2016 Apr 1;12(2):326-33. doi: 10.5114/aoms.2014.47881. Epub 2015 Jan 14.

  PMID: 27186176 BACKGROUND

• Tully PJ, Baker RA, Winefield HR, Turnbull DA. Depression, anxiety disorders and Type D personality as risk factors for delirium after cardiac surgery. Aust N Z J Psychiatry. 2010 Nov;44(11):1005-11. doi: 10.3109/00048674.2010.495053.

  PMID: 21034183 BACKGROUND

• Stenman M, Sartipy U. Depression Screening in Cardiac Surgery Patients. Heart Lung Circ. 2019 Jun;28(6):953-958. doi: 10.1016/j.hlc.2018.04.298. Epub 2018 May 16.

  PMID: 29871802 RESULT

• Manea L, Gilbody S, McMillan D. Optimal cut-off score for diagnosing depression with the Patient Health Questionnaire (PHQ-9): a meta-analysis. CMAJ. 2012 Feb 21;184(3):E191-6. doi: 10.1503/cmaj.110829. Epub 2011 Dec 19.

  PMID: 22184363 RESULT

• Sadik S, Bradley M, Al-Hasoon S, Jenkins R. Public perception of mental health in Iraq. Int J Ment Health Syst. 2010 Oct 11;4:26. doi: 10.1186/1752-4458-4-26.

  PMID: 20937100 RESULT

• Murphy BM, Elliott PC, Higgins RO, Le Grande MR, Worcester MU, Goble AJ, Tatoulis J. Anxiety and depression after coronary artery bypass graft surgery: most get better, some get worse. Eur J Cardiovasc Prev Rehabil. 2008 Aug;15(4):434-40. doi: 10.1097/HJR.0b013e3282fbc945.

  PMID: 18677168 RESULT

• Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. doi: 10.1046/j.1525-1497.2001.016009606.x.

  PMID: 11556941 RESULT

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Central Study Contacts

Abdul-Ilah R. Khamis

CONTACT

+9647838571013; allaabed987@ced.nahrainuniv.edu.iq

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 10, 2024
• First Posted: December 16, 2024
• Study Start: April 20, 2025
• Primary Completion: June 1, 2025
• Study Completion: June 12, 2025
• Last Updated: March 18, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)