Assessment of Pre Hospital Rescue Intervention for Seizure in Pediatric Patients

NCT06723431 | Not Yet Recruiting

• 1 other identifier: Pre hospital TTT of seizure
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

1. 1.Evaluation of pre hospital rescue intervention of seizure management.
2. 2.To investigate the type of rescue medication, Efficacy, route of administration, Side effects of this drug, frequency and Indication of its use.

Conditions

Seizure

Keywords

seizure in pediatric patients

Outcome Measures

Primary Outcomes (1)

• Aim of the study

  1. Evaluation of prehospital rescue intervention of seizure management. 2. To investigate the type of rescue medication, 1. it's Efficacy. 2. it's route of administration. 3. Side effects of this drug. 4. frequency . 5. Indication of it's use.

  Baseline

Secondary Outcomes (1)

• Seizure triggers

  Baseline

Study Arms (1)

(A)Patient with seizure received rescue interventional (B) Patient with seizure didn't receive it

We will do 2 groups : Group A: Patient with recurrent attack of seizure and with prolonged seizure with prescribed treatment at home, Patients aged from 2 years to 18 years, Received rescue intervention. Group B: Patient with recurrent attack of seizure and with prolonged seizure without prescribed treatment at home, Patients aged from 2 years to 18 years, didn't Received rescue intervention.

Eligibility Criteria

• Age: 2 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

pediatric with seizure and take rescue intervention prehospital

You may qualify if:

• Patient with recurrent attack of seizure and with prolonged seizure with prescribed treatment at home.
• Patients aged from 2 years to 18 years

You may not qualify if:

• First attack of seizure
• condition mimic epilepsy

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Laccheo I, Sonmezturk H, Bhatt AB, Tomycz L, Shi Y, Ringel M, DiCarlo G, Harris D, Barwise J, Abou-Khalil B, Haas KF. Non-convulsive status epilepticus and non-convulsive seizures in neurological ICU patients. Neurocrit Care. 2015 Apr;22(2):202-11. doi: 10.1007/s12028-014-0070-0.

  PMID: 25246236 BACKGROUND

• Silbergleit R, Durkalski V, Lowenstein D, Conwit R, Pancioli A, Palesch Y, Barsan W; NETT Investigators. Intramuscular versus intravenous therapy for prehospital status epilepticus. N Engl J Med. 2012 Feb 16;366(7):591-600. doi: 10.1056/NEJMoa1107494.

  PMID: 22335736 BACKGROUND

• Cloyd J, Haut S, Carrazana E, Rabinowicz AL. Overcoming the challenges of developing an intranasal diazepam rescue therapy for the treatment of seizure clusters. Epilepsia. 2021 Apr;62(4):846-856. doi: 10.1111/epi.16847. Epub 2021 Feb 22.

  PMID: 33617690 BACKGROUND

• Young GB, Claassen J. Nonconvulsive status epilepticus and brain damage: further evidence, more questions. Neurology. 2010 Aug 31;75(9):760-1. doi: 10.1212/WNL.0b013e3181f32141. No abstract available.

  PMID: 20805520 BACKGROUND

MeSH Terms

Conditions

Seizures

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Samah Gamal Hussien, doctor

CONTACT

+201025389433; samahelewa085@gmail.com

Fatma abdelfatah ali

CONTACT

0 1006347038

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assessment of pre hospital rescue intervention for seizure in pediatric patients

Study Record Dates

• First Submitted: October 1, 2024
• First Posted: December 9, 2024
• Study Start: January 1, 2025
• Primary Completion: October 1, 2025
• Study Completion: November 1, 2025
• Last Updated: December 9, 2024

Record last verified: 2024-12