NCT06721741

Brief Summary

This pilot study aims to compare the clinical and radiographic success of Bioflex (Nusmile) crowns Versus Stainless-steel crowns in restoring decayed primary molars.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
5mo left

Started Jun 2025

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress70%
Jun 2025Oct 2026

First Submitted

Initial submission to the registry

October 2, 2024

Completed
2 months until next milestone

First Posted

Study publicly available on registry

December 6, 2024

Completed
6 months until next milestone

Study Start

First participant enrolled

June 1, 2025

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2026

Expected
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Last Updated

February 17, 2025

Status Verified

November 1, 2024

Enrollment Period

1 year

First QC Date

October 2, 2024

Last Update Submit

February 13, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Patient relevant criteria

    1. Clinically Success if: No clinical signs or symptoms like: * Pain * Dental Abscess/Swelling * Sinus Tract/ Fistula * Mobility 2. Radiographically Success if: No pathology visible on x-ray like: * Internal/External Root Resorption * Peri-radicular Radiolucency * Furcation Involvement * Periapical Pathosis

    1 Year

Secondary Outcomes (1)

  • Crown Relevant Criteria

    1Year

Study Arms (2)

Stainless steel crown

ACTIVE COMPARATOR

Control group

Other: Stainless steel crowns

Bioflex crown

EXPERIMENTAL

Intervention group

Other: Nusmile bioflex crowns

Interventions

The Bioflex crown is a new synthetic crown that has been introduced in pediatric practice. This crown is believed to offer better adaptation, durability, and ease of handling, along with improved aesthetic properties when compared to conventional crowns

Bioflex crown

Preformed metal crowns are a popular and affordable option as a treatment for dental caries. They offer full crown coverage and help to prevent recurrent caries. However, their aesthetic limitation is a notable drawback

Stainless steel crown

Eligibility Criteria

Age4 Years - 7 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Clinical Criteria:
  • Children from age 4-7.
  • Cooperative children and willing for follow-up visits.
  • Mandibular second Primary molars with multi-surface caries
  • Radiographic criteria:
  • Mandibular second Primary molars with at least two-thirds of the root remaining.

You may not qualify if:

  • General Criteria:
  • <!-- -->
  • Unable to attend follow-up visits
  • Refuse to participate in the study
  • Uncooperative child
  • Clinical Criteria:
  • Tooth with grade II or grade III mobility
  • Children with bruxism
  • Pulpally involved teeth
  • Radiographic Criteria:
  • Tooth with pathological root resorption
  • Teeth with root caries

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Central Study Contacts

Hajer Ahmed Mousa

CONTACT

Manal Ahmed Elsayed

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

October 2, 2024

First Posted

December 6, 2024

Study Start

June 1, 2025

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

October 1, 2026

Last Updated

February 17, 2025

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will not share