NCT06720480

Brief Summary

This study aims to develop a nuanced understanding of thalassemia severity in Upper Egypt by integrating various clinical parameters beyond transfusion frequency. By doing so, it seeks to enhance patient management and ultimately improve quality of life for those affected by this condition.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
85

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2024

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 3, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 6, 2024

Completed
25 days until next milestone

Study Start

First participant enrolled

December 31, 2024

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

December 6, 2024

Status Verified

December 1, 2024

Enrollment Period

11 months

First QC Date

December 3, 2024

Last Update Submit

December 3, 2024

Conditions

Thalassaemia

Keywords

Thalassaemia severity score

Outcome Measures

Primary Outcomes (1)

  • Scoring thalassaemia severity

    1year

Interventions

Homglobin ElectrophoresisDIAGNOSTIC_TEST

To diagnose thalassaemia \&best method to control disease progress

Eligibility Criteria

Age6 Months - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Children from 6month till 18years who have thalassaemia

You may qualify if:

  • \- Children and adolescents aged from 18 month to 18 year old. Those with thalassemia

You may not qualify if:

  • Non Thalassaemia children

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Danjou F, Francavilla M, Anni F, Satta S, Demartis FR, Perseu L, Manca M, Sollaino MC, Manunza L, Mereu E, Marceddu G, Pissard S, Joly P, Thuret I, Origa R, Borg J, Forni GL, Piga A, Lai ME, Badens C, Moi P, Galanello R. A genetic score for the prediction of beta-thalassemia severity. Haematologica. 2015 Apr;100(4):452-7. doi: 10.3324/haematol.2014.113886. Epub 2014 Dec 5.

    PMID: 25480500RESULT

MeSH Terms

Conditions

Thalassemia

Condition Hierarchy (Ancestors)

Anemia, Hemolytic, CongenitalAnemia, HemolyticAnemiaHematologic DiseasesHemic and Lymphatic DiseasesHemoglobinopathiesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Shereen Mansour Galal, Associate professor

    Assiut University

    STUDY DIRECTOR

Central Study Contacts

AlZhraa Gaber Mohamed, Master degree

CONTACT

800-555-5555alzhraagaber@gmail.com

Khalid Ibrahim Abdrahman El-sayeh, Proffesour

CONTACT

0100 548 4357K.elsayd@aun.edu.eg

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident doctor

Study Record Dates

First Submitted

December 3, 2024

First Posted

December 6, 2024

Study Start

December 31, 2024

Primary Completion

December 1, 2025

Study Completion

December 31, 2025

Last Updated

December 6, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share