NCT06715566

Brief Summary

The main goal of this quasi-experimental study is to prevent the negative consequences of mobility impairments after stroke. These include recurrent strokes, general deconditioning, and overweight on the physical side, and dependency, isolation, caregiver strain, and reduced quality of life from a psycho-social perspective. ActForStroke, a combination of high-intensity gait training and subsequent remote coaching and activity monitoring, will contribute to more steps, higher activity levels and increased participation. ActForStroke requires minimal extra resources and can easily be implemented within existing staffing levels. The investigators want to examine if patients who participate in the ActForStroke intervention are more active one year after stroke. Patients with stroke will either participate in a combined intervention of high-intensity gait training and subsequent coaching to facilitate physical and social activity or receive standard care.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
8mo left

Started Jan 2025

Typical duration for not_applicable

Geographic Reach
1 country

10 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress67%
Jan 2025Dec 2026

First Submitted

Initial submission to the registry

November 18, 2024

Completed
16 days until next milestone

First Posted

Study publicly available on registry

December 4, 2024

Completed
28 days until next milestone

Study Start

First participant enrolled

January 1, 2025

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2026

Expected
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

December 4, 2024

Status Verified

November 1, 2024

Enrollment Period

1.6 years

First QC Date

November 18, 2024

Last Update Submit

December 3, 2024

Conditions

Keywords

strokeactivitygaittrainingcoaching

Outcome Measures

Primary Outcomes (1)

  • Physical activity

    The main outcome measure will be the average number of non-sedentary minutes per day measured during 3 days of sensor measurements. The SENS motion® wearable sensor will be used to monitor physical activity during 3 days. The SENS motion® registers acceleration on x,y,z axes.

    From baseline up to 12 months after stroke, 4 assessments will be conducted at inclusion to the study, 2 weeks after inclusion, 6 months and 12 months after stroke.

Secondary Outcomes (9)

  • 10m walk test

    Two assessments: At inclusion to the study, 2 weeks after inclusion.

  • Timed-up-and-go

    Two assessments: At inclusion to the study, 2 weeks after inclusion.

  • 6 minutes walk test

    Two assessments: At inclusion to the study, 2 weeks after inclusion.

  • Sit-to-stand test

    Two assessments: At inclusion to the study, 2 weeks after inclusion.

  • Five-level EQ5d (EQ5D) (there is no full name)

    Four assessments up to 12 months after stroke: At inclusion, after two weeks, 6 months and 12 months after stroke.

  • +4 more secondary outcomes

Study Arms (2)

ActForStroke

EXPERIMENTAL

A combination of high-intensity gait training and coaching to encourage physical and social activity.

Behavioral: ActForStroke

Standard care

ACTIVE COMPARATOR

Standard care usually provided

Behavioral: Standard care

Interventions

ActForStrokeBEHAVIORAL

ActForStroke is a combination of 10 sessions high-intensity gait training and subsequent with up 7 coaching sessions until 1 year after stroke.

ActForStroke
Standard careBEHAVIORAL

Usual rehabilitation services

Standard care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • ≥18 years
  • stroke within the last 6 months
  • able to give informed consent according to the neurorehabilitation team's evaluation and/or cognitive testing
  • receiving rehabilitation for post-stroke functional impairments.

You may not qualify if:

  • Use of bracing or instrumentation (e.g. ventilator) that limits walking independence in walking outdoors and on stairs
  • Functional Ambulation Category (FAC) at admission = 5 (independent ambulator on all surfaces)
  • uncontrolled cardiopulmonary, metabolic, infectious or psychiatric disorders
  • any disorder that prevented walking \> 50 meters prior to injury

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Genoptræning Aalborg Municipality

Aalborg, Denmark, 9000, Denmark

Location

Neuroenhed Nord Brønderslev

Brønderslev, Denmark, 9700, Denmark

Location

Neurocentet København

Copenhagen, Denmark, 2100, Denmark

Location

Hammel Neurocenter and University Research Clinic, Denmark

Hammel, Denmark, 8000, Denmark

Location

Favrskov Municipality

Hammel, Denmark, 8450, Denmark

Location

Jammerbugt Municipality Neuroteam

Jammerbugt, Denmark, 9460, Denmark

Location

Skive Sundhedsafdeling

Skive, Denmark, 7800, Denmark

Location

Svendborg Neurorehabilitation

Svendborg, Denmark, 5700, Denmark

Location

Thisted Municipality

Thisted, Denmark, 7700, Denmark

Location

Vejle Municipality

Vejle, Denmark, 7100, Denmark

Location

MeSH Terms

Conditions

StrokeMotor Activity

Interventions

Standard of Care

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesBehavior

Intervention Hierarchy (Ancestors)

Quality Indicators, Health CareQuality of Health CareHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Officials

  • Iris C. Brunner, Phd

    Aarhus University, Hammel Neurocenter

    STUDY DIRECTOR
  • Gunhild M. Hansen, PhD

    University College Nord, Aalborg, Denmark

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Iris C. Brunner, PhD

CONTACT

Gunhild M. Hansen, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Parallel group quasi-experimental design
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 18, 2024

First Posted

December 4, 2024

Study Start

January 1, 2025

Primary Completion (Estimated)

July 31, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

December 4, 2024

Record last verified: 2024-11

Locations