NCT06714773

Brief Summary

The goal of this observational study is to assess the oncological outcomes in patients diagnosed with grade 2 chondrosarcoma, treated with intralesional curettage, stratified into two cohorts: those subjected to follow up monitoring and those who have undergone subsequent surgical intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 20, 2024

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2024

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2024

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

November 28, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

December 4, 2024

Completed
Last Updated

December 4, 2024

Status Verified

October 1, 2024

Enrollment Period

6 months

First QC Date

November 28, 2024

Last Update Submit

November 28, 2024

Conditions

Chondrosarcoma, Grade 2

Keywords

intralesional curettage

Outcome Measures

Primary Outcomes (2)

  • Tumor recurrence(%)

    It will be measured by: X-Rays, CT, MRI, PET CT scan

    3 months, 6 months, 1 year, 2 years, 5 years, 10 years

  • distant metastasis (%)

    It will be measured by: CT scan of the lungs, PET CT scan

    3 months, 6 months, 1 year, 2 years, 5 years, 10 years

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All adult patients with diagnosis of grade 2 chondrosarcoma of the appendiceal skeleton who underwent intralesional curettage surgery, treated between 01/01/2008 and 31/12/2020.

You may qualify if:

  • Patients with a diagnosis of grade 2 chondrosarcoma of the appendiceal skeleton in the definitive specimen;
  • Patients treated with intralesional curettage surgery;
  • Patients aged \>=18 years;
  • Patients who were treated between 01/01/2008 and 31/12/2020.

You may not qualify if:

  • Patients diagnosed with grade 1 or 3 chondrosarcoma on the histological diagnosis of the operative specimen.
  • Patients undergoing wide resection as the primary treatment.
  • Patients with less than 12 months follow-up.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, 40138, Italy

Location

MeSH Terms

Conditions

ChondrosarcomaLymphoma, Follicular

Condition Hierarchy (Ancestors)

Neoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsSarcomaLymphoma, Non-HodgkinLymphomaLymphoproliferative DisordersLymphatic DiseasesHemic and Lymphatic DiseasesImmunoproliferative DisordersImmune System Diseases

Study Officials

  • Andrea Sambri, MD

    IRCCS Azienda Ospedaliero-Universitaria di Bologna

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 28, 2024

First Posted

December 4, 2024

Study Start

January 20, 2024

Primary Completion

July 20, 2024

Study Completion

August 1, 2024

Last Updated

December 4, 2024

Record last verified: 2024-10

Locations

IT(1)