Role of Herbal Based Mouthwashes in Plaque Control

NCT06711263 | Not Yet Recruiting DMC

• 1 other identifier: Ajman Herbal mouthwash 2425
• Study Type: interventional
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care. Herbal treatments have gained popularity as a dietary supplement for illness prevention and as an alternative/complementary therapy in recent years. Herbal remedies come in a wide variety of forms and can be found on the market all over the world.

Conditions

Plaque Induced Gingival Disease

Keywords

plaque; gingival bleeding; resveratrol; miswak; tea tree oil; chlorhexidine

Outcome Measures

Primary Outcomes (1)

• plaque score

  To assess the plaque score

  From Baseline-pre-intervention to the end of treatment at 4 weeks

Secondary Outcomes (1)

• gingival bleeding score

  from pre-intervention to the end of the treatment at 4 weeks

Study Arms (4)

chlorhexidine

EXPERIMENTAL

Mouthwash will be used for these participants

Other: Mouthwash Product

Tea tree oil

ACTIVE COMPARATOR

Participants will use the mouthwash and plaque and gingival bleeding indice will be recorded at baseline, after 2 weeks and after 4 weeks

Other: Mouthwash Product

Reseverotriol

ACTIVE COMPARATOR

Participants will use the mouthwash and plaque and gingival bleeding indice will be recorded at baseline, after 2 weeks and after 4 weeks

Other: Mouthwash Product

Miswak

ACTIVE COMPARATOR

Participants will use the mouthwash and plaque and gingival bleeding indice will be recorded at baseline, after 2 weeks and after 4 weeks

Other: Mouthwash Product

Interventions

Mouthwash Product OTHER

* In the Initial Visit-Baseline, and subsequent visits, participants will be called in the morning. Morning hours will be chosen for examination, as it will reduce the risk of bias and also help in quantifying results. plaque and gingival scores will be recorded and the First herbal mouthwashes will be given, participants will also be provided new tooth-brushes (Oral B-soft). * They will be asked to follow their routine oral hygiene habits. They will be asked to come back after 2 weeks for plaque and gingival bleeding scores recording for the second visit and again after 2weeks post the second visit for the third and final visit to record their plaque and gingival bleeding scores.

Also known as: chlorhexidine, resverotriol, miswak, tea tree oil

Miswak; Reseverotriol; Tea tree oil; chlorhexidine

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients who are medically fit
• Patients with gingival inflammation not progressed into periodontitis (AAP classification
• Patients between the age of 18-60 years

You may not qualify if:

• Patients who are medically compromised
• Patient who have undergone a periodontal therapy for the past 3 months
• Patients who are healthy but have been using herbal mouthwashes

Sponsors & Collaborators

• Ajman University: lead

MeSH Terms

Conditions

Plaque, Amyloid; Gingival Hemorrhage

Interventions

Chlorhexidine; Tea Tree Oil

Condition Hierarchy (Ancestors)

Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Oral Hemorrhage; Mouth Diseases; Stomatognathic Diseases; Gingival Diseases; Periodontal Diseases; Hemorrhage; Pathologic Processes

Intervention Hierarchy (Ancestors)

Biguanides; Guanidines; Amidines; Organic Chemicals; Oils, Volatile; Oils; Lipids; Plant Oils; Plant Preparations; Biological Products; Complex Mixtures

Central Study Contacts

sudhir Rama Varma, MDS

CONTACT

971506595075; sudhir2002@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: participants are masked
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Model Details: In the Initial Visit-Baseline, and subsequent visits, participants will be called in the morning. Morning hours will be chosen for examination, as it will reduce the risk of bias and also help in quantifying results. plaque and gingival scores will be recorded and the First herbal mouthwashes will be given, participants will also be provided new tooth-brushes (Oral B-soft).

Study Record Dates

• First Submitted: November 26, 2024
• First Posted: December 2, 2024
• Study Start: December 20, 2024
• Primary Completion: February 20, 2025
• Study Completion: March 20, 2025
• Last Updated: December 2, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share