Effect of Hypertensive Drugs on Root Caries Among Senior Patients in Cairo University

NCT06709352 | Completed DMC

• 1 other identifier: Root Caries & Drugs
• Study Type: observational
• Target: 209
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this analytical cross-sectional study study is to evaluate the prevalence of root caries in senior patients of both genders age of 50 to 70 years old, taking antihypertensive drugs attending the Cairo University Dental Educational Hospital and to consider the association of root caries with antihypertensive drugs. Furthermore, to understand the relationship between risk indicators of root caries and saliva pH that can be a potential etiological factor. \- The main question it aims to answer is: In senior patients attending Cairo University Dental Educational Hospital, what is the prevalence of root caries among patients taking antihypertensive drugs, what are the related risk indicators and how do they correlate with salivary pH?

Conditions

Root Caries; Antihypertensive Drugs

Outcome Measures

Primary Outcomes (1)

• Prevalence of root caries in patients taking anti- hypertensive drugs.

  1. Prevalence of root caries measured by using the index of the root (R) 'ICDAS' assessment of caries lesions: Facial, mesial, distal, Lingual root surfaces of each tooth as one score/surface (decayed /filled) and its codes. 2. Unit of measurement is: * Score E and 0 will be considered as root caries free and the rest of scores will be counted as root caries, Scores expressed as frequency and Percentages. 3. The instrument used is: The root (R) ICDAS assessment of caries lesions using the Community Periodontal Index (CPI) probe with 0.5mm round tip. 4. Participants included: All participants under inclusion criteria.

  3 months

Secondary Outcomes (1)

• Associated risk indicator

  4 months

Interventions

non OTHER

non

Eligibility Criteria

• Age: 50 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* Senior patients, age group of 50-70 years old , attending in the diagnosis clinic at Conservative Dentistry department, faculty of dentistry, Cairo University Egypt, will be examined for their chief complaint. * Patients will be enrolled in this study if they are compatible with eligibility criteria.

You may qualify if:

• Senior patients, age group of 50-70 years old
• Positive subject acceptance for participation in the study
• Taking anti-hypertensive drugs
• Both gender
• Egyptian Nationals

You may not qualify if:

• Seniors with dental emergency 12
• Seniors with psychological problem
• Seniors with reported terminal illness or severe mental impairment in the medical records.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry

Cairo, Egypt

Location

Related Publications (4)

• Kumara-Raja B, Radha G. Prevalence of root caries among elders living in residential homes of Bengaluru city, India. J Clin Exp Dent. 2016 Jul 1;8(3):e260-7. doi: 10.4317/jced.52682. eCollection 2016 Jul.

  PMID: 27398175 BACKGROUND

• Gugnani N, Pandit IK, Srivastava N, Gupta M, Sharma M. International Caries Detection and Assessment System (ICDAS): A New Concept. Int J Clin Pediatr Dent. 2011 May-Aug;4(2):93-100. doi: 10.5005/jp-journals-10005-1089. Epub 2010 Apr 15.

  PMID: 27672245 BACKGROUND

• Langari SF, Hosseini SR, Bijani A, Jenabian N, Motalebnejad M, Mahmoodi E, Madani ZS, Sayadi F, Naghibi Sistani M, Ghadimi R, Baladi F, Hajimirzamohammad M, Mehryari M, Shirzad A. Association between antihypertensive drugs and the elderly's oral health- related quality of life: Results of Amirkola cohort study. Caspian J Intern Med. 2022 Summer;13(3):582-588. doi: 10.22088/cjim.13.3.582.

  PMID: 35974945 BACKGROUND

• Valtellini R, Ouanounou A. Management of the Hypertensive Dental Patient. J Can Dent Assoc. 2023 Mar;89:n2.

  PMID: 37098279 BACKGROUND

Related Links

• Biostatistics 102: quantitative data--parametric \& non-parametric tests
• Streckfus CF, Strahl RC, Welsh S. Anti-hypertension medications: an epidemiological factor in the prevalence of root decay among geriatric patients suffering from hypertension. Clinical Preventive Dentistry. 1990 Aug-Sep;12(3):26-29. PMID: 2150630.
• Jingyang Zhang, Edward Chin Lo et al, (2020), Epidemiology of dental root caries: a review of risk factors, FOMM J.
• Al-Harthy, N. , Qutiesha, A. et al, (2023) : A Preventive Strategy against Root Caries for the General Dentist: A Cross-sectional Clinical Study.Op Dent J, Volume 17.

MeSH Terms

Conditions

Root Caries

Condition Hierarchy (Ancestors)

Dental Caries; Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Nuha Abdelrahman Abdelhai Elhaj (DDS)

Study Record Dates

• First Submitted: November 22, 2024
• First Posted: November 29, 2024
• Study Start: February 1, 2025
• Primary Completion: April 1, 2025
• Study Completion: January 30, 2026
• Last Updated: March 23, 2026

Record last verified: 2026-03

Locations

EG (1)