NCT06707636

Brief Summary

This research seeks to improve the Midlife Black Women's Stress Reduction and Wellness Intervention (B-SWELL), a program designed to lower heart disease risk in midlife Black women. The B-SWELL leverages stress reduction to facilitate the adoption and adherence to healthier lifestyle behaviors. This research study will use choice to increase engagement and minimize the effect of social determinants of health on research participation among midlife Black women. A comparative clinical trial will be conducted. Midlife Black women (ages 45-64) who reside in the Greater Cincinnati area will be recruited for participation. Women are eligible if they self-identify as Black/ African American, are between the ages of 45-64, and are willing to commit to the requirements of the study (e.g., attend 8 weekly sessions and 4 phone interviews). Participants will be randomly placed (like the flip of a coin) into either the B-SWELL or WE group. Both the B-SWELL and WE groups are 8-week programs that focus on healthy lifestyle behaviors and heart disease awareness. Women will have the choice to participate in person or virtually. Survey phone interviews will be conducted at baseline, 8-, 12-, and 16-weeks. Data collected will provide information about adherence, healthy lifestyle behaviors, and cardiovascular health. Heart health will be measured using the American Heart Association's Life's Essential 8 metric. Outcome measures include heart disease awareness, Life's Essential 8 score, stress, self-efficacy, depressive symptoms, and symptoms.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for not_applicable

Timeline
1mo left

Started Oct 2024

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress96%
Oct 2024May 2026

Study Start

First participant enrolled

October 11, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 14, 2024

Completed
13 days until next milestone

First Posted

Study publicly available on registry

November 27, 2024

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2026

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2026

Expected
Last Updated

April 13, 2026

Status Verified

April 1, 2026

Enrollment Period

1.4 years

First QC Date

November 14, 2024

Last Update Submit

April 6, 2026

Conditions

Keywords

perceived stressheart disease risk factorslifestyle interventionbehavior changestrong woman syndromechoice

Outcome Measures

Primary Outcomes (1)

  • Life's Essential 8 (LE8) score

    Life's Essential 8 (LE8) is a recognized metric for cardiovascular health as defined by the American Heart Association. The LE8 score consists of 8 sub-measures. There are 4 lifestyle behaviors (Diet, Physical Activity, Nicotine Exposure and Sleep Health) and 4 health factors (BMI, Blood Lipids, Blood Glucose, and Blood Pressure). The total LE8 score is calculated as the average of the 8 individual component scores. Total scores range from 0 to 100 points. Higher scores correspond to better cardiovascular health.

    From baseline to 16 weeks

Secondary Outcomes (3)

  • Patient Health Questionnaire (PHQ-9)

    from baseline to 16 weeks.

  • Pittsburgh Sleep Quality Index (PSQI)

    From baseline to 16 weeks

  • researcher-developed symptoms check list

    From baseline to 16 weeks

Other Outcomes (3)

  • Perceived stress (PSS-10)

    from baseline to 16 weeks.

  • Genral Self Efficacy (GSE)

    From baseline to 16 weeks

  • Super Woman Syndrome

    baseline

Study Arms (2)

Black Women's Stress and Wellness (B-SWELL) arm

EXPERIMENTAL

The B-SWELL arm consists of 8-weekly sessions. Sessions last 90 minutes and focus on stress reduction, heart disease, and healthy lifestyle changes. The American Heart Association's Life's Essential 8 metrics are leveraged and culturally tailored in the B-SWELL materials. Participants will also receive personalized health coaching.

Behavioral: Experimental: Black Women's Stress and Wellness (B-SWELL) arm

Wellness (WE) arm

ACTIVE COMPARATOR

This is an attention control group. Participants placed in his arm will receive 8-weekly sessions focused on the Life's Essential 8 metrics. Sessions will last approximately 90 minutes.

Behavioral: Active Comparator: Wellness (WE) arm

Interventions

This is an attention control group. Participants placed in his arm will receive 8-weekly sessions focused on the Life's Essential 8 metrics.

Wellness (WE) arm

The B-SWELL arm consists of 8-weekly sessions. Sessions last 90 minutes and focus on stress reduction, heart disease, and healthy lifestyle changes. The American Heart Association's Life's Essential 8 metrics are leveraged and culturally tailored in the B-SWELL materials. Participants will also receive personalized health coaching.

Black Women's Stress and Wellness (B-SWELL) arm

Eligibility Criteria

Age45 Years - 64 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Identifies as Black/ African American
  • Age 45-64.
  • Willing to adhere to the study requirements.

You may not qualify if:

  • Incarcerated or on house arrest,
  • Diagnosed with terminal illness, severe mental illness, or dementia.
  • Unable or unwilling to participate in 8 weekly sessions and 4 phone interviews.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ohio State University

Cincinnati, Ohio, 45221, United States

Location

MeSH Terms

Conditions

Depression

Interventions

Health

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

Population Characteristics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

November 14, 2024

First Posted

November 27, 2024

Study Start

October 11, 2024

Primary Completion

February 28, 2026

Study Completion (Estimated)

May 31, 2026

Last Updated

April 13, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

This study will provide prospective survey data from a randomized pilot trial at four timepoints over a period of 16 weeks. The sample (N=64) consists of Black women ages 45-64. The data collected will include survey responses designed to assess viability of the optimized Midlife Black Women's Stress and Wellness intervention (B-SWELL). Surveys will include researcher developed tools (i.e., demographics, satisfaction, feedback, and symptoms check list), and seven validated tools (Cohen's Perceived Stress Scale, General Self-Efficacy scale, American Heart Association's Life's Essential 8 score, Perceived General Health scale, Patient Health Questionnaire, and Pittsburgh Sleep Quality Index). Coding, recodes, and analyses related to each tool will be performed according to instruction as they have been validated to ensure production of accurate results.

Shared Documents
STUDY PROTOCOL, ANALYTIC CODE
Time Frame
Data will be will placed in the generalist database, DRYAD in accordance with NIH recommendations, at the time of publication. Data will then remain in DRYAD in perpetuity.
Access Criteria
Studies registered in Dryad are assigned a citable digital object identifier (DOI) number. Studies can be searched by name, DOI identifier, or topic. Datasets in DRYAD are indexed by the Thomson-Reuters Data Citation Index and include schema.org mark-up to make them discoverable in Google Dataset Search. DRYAD also integrates with any SWORD/OAI-PMH compliant repository, allowing its records to be discoverable through additional third-party aggregators.
More information

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