Muscle Oxygenation, Functional Capacity and Frailty in Kidney Transplant Recipients with and Without Inspiratory Muscle Weakness
Comparison of Muscle Oxygenation, Functional Capacity, and Frailty in Kidney Transplant Recipients with and Without Inspiratory Muscle Weakness
1 other identifier
observational
30
1 country
1
Brief Summary
The aim of this study was to compare respiratory function, muscle oxygenation, functional capacity, peripheral muscle strength, body composition, and frailty in kidney transplant recipients with and without inspiratory muscle weakness.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Apr 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 6, 2024
CompletedFirst Submitted
Initial submission to the registry
November 19, 2024
CompletedFirst Posted
Study publicly available on registry
November 26, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2025
CompletedNovember 26, 2024
November 1, 2024
8 months
November 19, 2024
November 22, 2024
Conditions
Outcome Measures
Primary Outcomes (5)
Respiratory muscle strength
Maximal inspiratory pressure (MIP) will be measured using a portable mouth pressure measuring device.
1st day
Respiratory muscle strength
Maximal expiratory pressure (MEP) will be measured using a portable mouth pressure measuring device.
1st day
Functional capacity
Will be evaluated with 6 minute walk test.
1st day
Peripheral muscle strength
Knee extensor strength will be measured using a hand dynamometer.
1st day
Peripheral muscle strength
Hand grip strength will be measured using grip dynamometer.
1st day
Secondary Outcomes (7)
Forced expiratory volume in one second
1st day
Forced vital capacity
1st day
Forced expiratory volume in one second/forced vital capacity
1st day
Peak expiratory flow
1st day
Forced mid-expiratory flow
1st day
- +2 more secondary outcomes
Study Arms (2)
Patients with inspiratory muscle weakness
Patients without inspiratory muscle weakness
Eligibility Criteria
Kidney transplant recipients will be included.
You may qualify if:
- Patients with kidney transplantation
- At least 6 months after the kidney transplant
- Not having regular exercise habits
- Voluntary participation in the study
You may not qualify if:
- Having a musculoskeletal problem that may interfere with the tests
- Having neurological impairment
- Having chronic lung disease
- Having had any cardiovascular event in the last 6 months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hacettepe University
Ankara, Turkey (Türkiye)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
November 19, 2024
First Posted
November 26, 2024
Study Start
April 6, 2024
Primary Completion
December 1, 2024
Study Completion
August 1, 2025
Last Updated
November 26, 2024
Record last verified: 2024-11