NCT06704295

Brief Summary

This randomized controlled trial aims to examine the effects of high-impact e-cigarette advertisement features among young adults of various tobacco-use statuses. Previous research on examining the effects of e-cigarette advertisement features found that flavor-related features (e.g., flavor-associated product color, name and image, flavor sensation descriptor, and flavor choice claim) may have the largest impact on shaping young adults' perceptions and use intentions of e-cigarettes. No research so far has solely focused on examining the effects of those high-impact flavor-related advertisement features. The present study assessed the effects of high-impact flavor-related advertisement features, including flavor descriptor name, e-cigarette product color (which indicates flavors), flavor-related image, flavor sensation descriptor, and flavor choice claim on perceptions and behavioral intentions among a large online sample of young adults aged 18-30 who either smoke cigarettes or do not use tobacco products. The study is a six-group RCT with parallel assignments that will be delivered through an online self-administered questionnaire consisting of one session. Participants will be randomly assigned to one of six trial arms: 1) dark gray product with tobacco flavor name, 2) dark gray product with strawberry flavor name, 3) colorful (strawberry color) product with strawberry flavor name, 4) colorful (strawberry color) product with strawberry flavor name and strawberry image, 5) colorful (strawberry color) product with strawberry flavor name, strawberry image, strawberry flavor sensation descriptor, and 6) colorful (strawberry color) product with strawberry flavor name, strawberry image, strawberry flavor sensation descriptor, and flavor choice claim. Participants will be exposed to one advertisement corresponding to the assigned condition, and answer survey questions immediately after message exposure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,083

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 22, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 26, 2024

Completed
21 days until next milestone

Study Start

First participant enrolled

December 17, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 10, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 10, 2025

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

March 9, 2026

Completed
Last Updated

March 9, 2026

Status Verified

December 1, 2025

Enrollment Period

2 months

First QC Date

November 22, 2024

Results QC Date

December 7, 2025

Last Update Submit

February 16, 2026

Conditions

Keywords

E-cigarette advertisementVapingComplete switchingCigarette smoking cessationYoung adultsE-cigarette marketingTobacco policy

Outcome Measures

Primary Outcomes (2)

  • Intentions of Using the E-cigarette

    A single item measuring the intentions of using the e-cigarette shown in the ad, assessed immediately after exposure (exposure took approximately 12 seconds). Response options are from 0 (Extremely unlikely ) to 10 (Extremely likely).

    Immediately after exposure

  • Intentions of Switching Completely to the E-cigarette

    A single item measuring participants' intentions of switching completely to the e-cigarette shown in the ad, assessed immediately after exposure (exposure took approximately 12 seconds). Response options are from 0 (Extremely unlikely ) to 10 (Extremely likely). This question is only asked among those who smoke cigarettes.

    Immediately after exposure

Secondary Outcomes (5)

  • Intentions of Using the E-cigarette Compared to Cigarettes

    Immediately after exposure

  • Intentions of Using the E-cigarette Compared to Other E-cigarettes

    Immediately after exposure

  • Ad Appeal

    Immediately after exposure

  • Perceived Absolute Harm of Using the E-cigarette

    Immediately after exposure

  • Perceived Absolute Addictiveness of Using the E-cigarette

    Immediately after exposure

Other Outcomes (3)

  • Sensory Appeal of the E-cigarette

    Immediately after exposure

  • Positive Expectancy of Using the E-cigarette

    Immediately after exposure

  • Negative Expectancy of Using the E-cigarette

    Immediately after exposure

Study Arms (6)

Control ad: Dark gray product with tobacco flavor name

OTHER
Behavioral: Control ad with dark gray product with tobacco flavor name

Dark gray product with strawberry flavor name

EXPERIMENTAL
Behavioral: Dark gray product with strawberry flavor name

Colorful (strawberry color) product with strawberry flavor name

EXPERIMENTAL
Behavioral: Colorful (strawberry color) product with strawberry flavor name

Colorful (strawberry color) product with strawberry flavor name and strawberry image

EXPERIMENTAL
Behavioral: Colorful (strawberry color) product with strawberry flavor name and image

Colorful (strawberry color) product with strawberry flavor features

EXPERIMENTAL

Colorful (strawberry color) product with strawberry flavor name + strawberry image + strawberry flavor sensation descriptor

Behavioral: Colorful (strawberry color) product with strawberry flavor features

Colorful (strawberry color) product with strawberry flavor features and choice claim

EXPERIMENTAL

Colorful (strawberry color) product with strawberry flavor name + strawberry image + strawberry flavor sensation descriptor + flavor choice claim

Behavioral: Colorful (strawberry color) product with strawberry flavor features and choice claim

Interventions

The e-cigarette ad with a dark gray product with a strawberry flavor name

Dark gray product with strawberry flavor name

The e-cigarette ad with a colorful (strawberry color) product with strawberry flavor name

Colorful (strawberry color) product with strawberry flavor name

The e-cigarette advertisement with colorful (strawberry color) product with strawberry flavor name, strawberry image, and strawberry flavor sensation descriptor

Colorful (strawberry color) product with strawberry flavor features

The e-cigarette ad with colorful (strawberry color) product with strawberry flavor name, strawberry image, strawberry flavor sensation descriptor, and flavor choice claim

Colorful (strawberry color) product with strawberry flavor features and choice claim

The e-cigarette ad with a dark gray product with a tobacco flavor name

Control ad: Dark gray product with tobacco flavor name

The e-cigarette ad with colorful (strawberry color) product with strawberry flavor name and strawberry image

Colorful (strawberry color) product with strawberry flavor name and strawberry image

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Three groups of young adult subjects will be included in the study. The first group is those who are exclusive cigarette smokers (n=1000), defined as those who have smoked at least 100 cigarettes in their lifetime and have smoked at least one cigarette in the past 30 days but have not used e-cigarettes in the past 30 days. The second group is those who are dual users of cigarettes and e-cigarettes (n=1000). Those in this group have smoked more than 100 cigarettes in their lifetime and have smoked a cigarette and also used an e-cigarette in the past 30 days. The third group is those who are non-tobacco users (n=1000), defined as those who have never used any tobacco product before or have never "regularly" used tobacco products before and are currently not using any tobacco products (in the past 30 days).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rutgers University

New Brunswick, New Jersey, 08901, United States

Location

MeSH Terms

Conditions

VapingTobacco Use Cessation

Interventions

Pharmaceutical Preparations

Condition Hierarchy (Ancestors)

SmokingBehaviorHealth Behavior

Results Point of Contact

Title
Dr. Chen-Sankey
Organization
Rutgers University School of Public Health

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

November 22, 2024

First Posted

November 26, 2024

Study Start

December 17, 2024

Primary Completion

February 10, 2025

Study Completion

February 10, 2025

Last Updated

March 9, 2026

Results First Posted

March 9, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations