NCT06701747

Brief Summary

This retrospective study was designed to develop a preoperative nomogram, validated both internally and externally, to supply an individual and precise tool for predicting the probability that patients will require perioperative transfusion therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11,197

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2023

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2024

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

November 15, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 22, 2024

Completed
Last Updated

November 22, 2024

Status Verified

November 1, 2024

Enrollment Period

8 months

First QC Date

November 15, 2024

Last Update Submit

November 20, 2024

Conditions

Massive TransfusionNomogram Model

Keywords

Massive transfusionRed blood cellsNomogramNon-cardiac surgeryPatient blood management

Outcome Measures

Primary Outcomes (1)

  • RBCs transfusion volume

    The total volume of RBCs transfused within 24 from the start of transfusion.

    Up to 24 hours after transfusion

Study Arms (2)

High-dose group

Receive RBCs transfusion over 1600mL

No-high-dose group

Receive RBCs transfusion under 1600mL

Eligibility Criteria

Age14 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

This retrospective study included 【】patients who received RBCs transfusion during non-cardiac surgery at West China Hospital between January 2018 and June 2024.

You may qualify if:

  • Patients undergoing non-cardiac surgery during hospitalization.
  • Patients receiving allogeneic RBCs transfusion within 24 hours during and after surgery.

You may not qualify if:

  • Age under 15 years.
  • Patients with incomplete clinical data.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

West China Hospital, Sichuan University

Chengdu, Sichuan, 610041, China

Location

Study Officials

  • Ren Liao, M.D.

    West China Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate professor

Study Record Dates

First Submitted

November 15, 2024

First Posted

November 22, 2024

Study Start

September 1, 2023

Primary Completion

May 1, 2024

Study Completion

July 31, 2024

Last Updated

November 22, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)