Hemodynamic Parameters in People With Atherosclerotic Vascular Disease Referred to a Secondary Prevention and Cardiovascular Rehabilitation Program

NCT06701032 | Active Not Recruiting

• 1 other identifier: CISSSCA-2025-1208
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The main purpose of this study is to evaluate the hemodynamic changes in the forefoot of patients with coronary, cerebrovascular or peripheral atherosclerotic disease referred a 12-week cardiovascular rehabilitation program (PREV program). Also, this study will describe the characteristics of patients admitted to the PREV program and their evolutions in terms of favorable, unfavorable outcomes and complications and up to one year after completion of the program.

Conditions

Peripheral Artery Disease (PAD); Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)); Cerebrovascular Atherosclerosis

Keywords

cardiovascular rehabilitation; supervised exercise therapy; secondary prevention; cardiovascular secondary prevention; cardiovascular rehabilitation program; hemodynamics of lower limbs; toe pressure measurement

Outcome Measures

Primary Outcomes (3)

• Change in toe pressure measurement

  Results will be measured in mm Hg

  Change from baseline to 12 weeks

• Change in the toe-brachial index

  Change from baseline to 12 weeks

• Change in the ankle-brachial index

  Change from baseline to 12 weeks

Secondary Outcomes (2)

• Change in 6-minute walk test (6MWT)

  Change from Baseline to 12 weeks

• Short Form Health Survey 36 (SF-36)

  Change from baseline to 12 weeks

Study Arms (1)

Cardiovascular rehabilitation program

EXPERIMENTAL

Other: Cardiovascular rehabilitation program

Interventions

Cardiovascular rehabilitation program OTHER

The cardiovascular rehabilitation program consists of a 12 weeks supervised exercises therapy (either in person or in tele-care)

Cardiovascular rehabilitation program

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Any individual aged 18 years and older who has been diagnosed with peripheral artery disease, coronary artery disease, angina, ischemic heart failure, transient ischemic attack or ischemic stroke (non-cardioembolic, non-hemorrhagic);
• Have been admitted to the PREV program;

You may not qualify if:

• Being not able to give written informed consent;

Sponsors & Collaborators

• Laval University: lead
• CISSS de Chaudière-Appalaches: collaborator

Study Sites (1)

CLSC de Lévis - Programme PREV du CISSS de Chaudière-Appalaches

Lévis, Quebec, G6V 0M4, Canada

Location

MeSH Terms

Conditions

Peripheral Arterial Disease; Coronary Artery Disease; Angina Pectoris; Myocardial Infarction

Condition Hierarchy (Ancestors)

Atherosclerosis; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases; Peripheral Vascular Diseases; Coronary Disease; Myocardial Ischemia; Heart Diseases; Chest Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Infarction; Ischemia; Pathologic Processes; Necrosis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 20, 2024
• First Posted: November 22, 2024
• Study Start: November 25, 2024
• Primary Completion: August 29, 2025
• Study Completion: March 1, 2026
• Last Updated: August 22, 2025

Record last verified: 2025-08

Locations

CA (1)