Value of Speckle Tracking Echocardiography Inflammatory Bowel Disease Patients

NCT06695065 | Not Yet Recruiting

• 1 other identifier: Echocardiogray in IBD
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Value of speckle tracking echocardiography in early assessment of cardiac function in inflammatory bowel disease .

Conditions

Echocardiography; Inflammatory Bowel Diseases; Cardiac Function

Outcome Measures

Primary Outcomes (2)

• Subclincal cardiovascular events in IBD patients.

  Assessment the predictive ability of Speckle TRACKING Echocardiograpy in development of subclinical cardiovascular events in IBD patients.

  through study completion, an average of 2 year

• Relation between isease activity and cardiac function

  Evaluation of the relationship between disease activity and cardiac function as measured by Speckle tracking Echocardiograpy.

  through study completion, an average of 2 year

Secondary Outcomes (1)

• correlation of Speckle TRACKING Echocardiograpy findings with traditional echocardiographic parameters

  through study completion, an average of 1 year

Study Arms (2)

Study group adult with ulcerative colitis

50 Adult patients with ulcerative colitis

control group

50 age and sex matched control group.

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

History: Demographic data; age, sex. History of the disease: onset, duration, medication. Family history of disease. History of comorbidities: hypertension, diabetes, ischemic heart diseases. Laboratory investigations: Fasting blood glucose, 2 hr postprandial and glycated haemoglobin A1c (HbA1c). Lipid profile: LDL, HDL, triglyceride, cholesterol. Inflammatory markers: CRP, ESR Complete blood picture Evaluation of Disease Severity Partial Mayo score consists three of the four components of the standard Mayo score, excluding endoscopic findings (stool frequency, rectal bleeding and physician's global assessment). Each component is assigned a score of 0-3, and total score ranges from 0 to 9 for each patient. -Echocardiographic Examination

You may qualify if:

• Age (18-60) yrs.
• Both sexes.
• Patients with IBD either in active form or in remission.

You may not qualify if:

• Patients with ischemic heart disease. -Patients with other comorbidities affecting heart as uncontrolled hypertension or diabetes. -
• Pregnant females.
• Malignancy

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Inflammatory Bowel Diseases

Condition Hierarchy (Ancestors)

Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases

Central Study Contacts

Asmaa Abdelshafy Mohamed

CONTACT

0109950131; Asma.shafy@aun.edu.eg

Noor el_deen Abdelazeem Mohamed

CONTACT

0100503518; noorelhefny@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physician

Study Record Dates

• First Submitted: November 14, 2024
• First Posted: November 19, 2024
• Study Start: October 1, 2025
• Primary Completion: March 1, 2026
• Study Completion (Estimated): December 1, 2027
• Last Updated: October 2, 2025

Record last verified: 2024-11