The Impact of Glycemic Control on Rheumatoid Arthritis Disease Activity on Diabetic Patients

NCT06691997 | Not Yet Recruiting

• 1 other identifier: DM and Rheumatoid Arthritis
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of DM is unclear in RA but most prior data suggest that DM or insulin resistance in RA has risen because of activation of the immune system and/or RA therapy . Besides, RA causes joints to become stiff, swollen, and agonizing. As a result, the patient may not want to exercise or move. One study found that 42% of people with RA are not physically active. the aim of this study is To evaluate the glycemic status among RA patients with Type 2 diabetes and its association with disease activity.

Conditions

Rheumatoid Arthritis (RA; Diabetes Mellitus

Keywords

glycemic control

Outcome Measures

Primary Outcomes (1)

• Fasting blood glucose

  correlation between type 2 diabetes control and rheumatoid arthritis activity

  baseline

Study Arms (1)

group 1

RA patients with Type 2 diabetes

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients above age of 18 years old diagnosed with Rheumatoid Arthritis and DM

You may qualify if:

• type 2 diabetic patients
• rheumatoid arthritis patients

You may not qualify if:

• gestional diabetes
• type 1 diabetic patients

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut university

Asyut, Egypt

Location

Related Links

• Wasserman A. Rheumatoid Arthritis: Common Questions About Diagnosis and Management. Am Fam Physician. 2018 Apr 1;97(7):455-462. PMID: 29671563.
• Almutairi KB, Nossent JC, Preen DB, Keen HI, Inderjeeth CA. The Prevalence of Rheumatoid Arthritis: A Systematic Review of Population-based Studies. J Rheumatol. 2021 May;48(5):669-676. doi: 10.3899/jrheum.200367. Epub 2020 Oct 15. PMID: 33060323.
• Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Meas
• Schoels M, Knevel R, Aletaha D, Bijlsma JWJ, Breedveld FC, Boumpas DT, Burmester G, Combe B, Cutolo M, Dougados M, Emery P, van der Heijde D, Huizinga TWJ, Kalden J, Keystone EC, Kvien TK, Martin-Mola E, Montecucco C, de Wit M, Smolen JS. Evidence for tr
• Jiang P, Li H, Li X. Diabetes mellitus risk factors in rheumatoid arthritis: a systematic review and meta-analysis. Clin Exp Rheumatol. 2015 Jan-Feb;33(1):115-21. Epub 2014 Dec 22. PMID: 25535750.

MeSH Terms

Conditions

Arthritis, Rheumatoid; Diabetes Mellitus

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Ahmed khedr Nady

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ahmed khedr Nady

CONTACT

+201097613616; ahmed.16266234@med.aun.edu.eg

Eman Mohamed Ibrahim, Lecturer

CONTACT

+201007179120; emanmibrahem@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecture

Study Record Dates

• First Submitted: October 27, 2024
• First Posted: November 18, 2024
• Study Start: December 12, 2024
• Primary Completion (Estimated): November 14, 2026
• Study Completion (Estimated): June 1, 2027
• Last Updated: November 18, 2024

Record last verified: 2024-11

Locations

EG (1)