NCT06689761

Brief Summary

This study investigates whether taking daily collagen peptides, combined with long-term endurance or concurrent training can enhance running economy through muscle and/or tendon adaptations.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 12, 2024

Completed
1 day until next milestone

Study Start

First participant enrolled

November 13, 2024

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 14, 2024

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2025

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2025

Completed
Last Updated

November 14, 2024

Status Verified

November 1, 2024

Enrollment Period

6 months

First QC Date

November 12, 2024

Last Update Submit

November 12, 2024

Conditions

Collagen Supplementation

Keywords

Running economycollagen supplementation

Outcome Measures

Primary Outcomes (4)

  • One-hour time trial performance

    Participants run an hour on the track outside as far as possible

    Baseline and after 12 weeks

  • Achilles tendon cross sectional-area

    Ultrasound

    Baseline and after 12 weeks

  • Achilles and Patellar tendon Stiffness

    Ultrasound + isokinetic dynamometer

    Baseline and after 12 weeks

  • VO2max

    treadmill with spirometry

    Baseline and after 12 weeks

Secondary Outcomes (5)

  • Body composition

    Baseline and after 12 weeks

  • Achilles tendon stress, strain, Young's modulus

    Baseline and after 12 weeks

  • Patellar tendon strain

    Baseline and after 12 weeks

  • RER, VT1, VT2, LTP1, LTP2, HFrel., FATox.

    Baseline and after 12 weeks

  • Achilles tendon echointensity

    Baseline and after 12 weeks

Other Outcomes (1)

  • Energy and macronutrient intake

    Baseline and after 12 weeks

Study Arms (4)

ColCT

EXPERIMENTAL

Dietary Supplement: Collagen Participants ingest 15 grams specific collagen peptides daily \+ Concurrent training 12 weeks, 3x/week

Dietary Supplement: ColCT

PlaCT

PLACEBO COMPARATOR

Dietary Supplement: Placebo Participants ingest 15 grams of a placebo daily \+ Concurrent training 12 weeks, 3x/week

Dietary Supplement: PlaCT

ColET

EXPERIMENTAL

Dietary Supplement: Collagen Participants ingest 15 grams specific collagen peptides daily \+ Endurance training 12 weeks, 3x/week

Dietary Supplement: ColET

PlaET

PLACEBO COMPARATOR

Dietary Supplement: Collagen Participants ingest 15 grams of placebo daily \+ Endurance training 12 weeks, 3x/week

Dietary Supplement: PlaET

Interventions

ColCTDIETARY_SUPPLEMENT

Dietary Supplement: Collagen Participants ingest 15 grams of specific collagen peptides daily

ColCT
ColETDIETARY_SUPPLEMENT

Dietary Supplement: Collagen Participants ingest 15 grams of specific collagen peptides daily

ColET
PlaCTDIETARY_SUPPLEMENT

Dietary Supplement: Placebo. Participants ingest 15 grams of placebo daily

PlaCT
PlaETDIETARY_SUPPLEMENT

Dietary Supplement: Placebo. Participants ingest 15 grams of placebo daily

PlaET

Eligibility Criteria

Age18 Years - 40 Years
Sexmale(Gender-based eligibility)
Gender Eligibility Detailsmen
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Male gender Age 18-40 years No subjective symptoms during physical exertion BMI of 18.5 to 26 Stable weight and dietary habits No extensive strength/endurance training (less than 3 hours per week) No contraindications to physical exertion according to ACSM guidelines No contraindications to supplemental nutrition or ergogenic supplements

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre for Sport Science and University Sports, Department of Sport and Human Movement Science

Vienna, Vienna, 1150, Austria

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Kevin Bischof Bakk., BSc., MSc., MBA

Study Record Dates

First Submitted

November 12, 2024

First Posted

November 14, 2024

Study Start

November 13, 2024

Primary Completion

May 1, 2025

Study Completion

May 30, 2025

Last Updated

November 14, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will not share

Locations

AU(1)