Effect of a Plant Based Nootropic on Perceptual Decision Making.
Effect of a Plant-based Nootropic Supplement on Perceptual Decision-making and Brain Network Interdependencies: a Randomised, Double-blinded and Placebo-controlled Study.
1 other identifier
interventional
37
1 country
1
Brief Summary
Nootropics are a group of medicinal substances purported to improve important cognitive functions such as learning, focus and memory. Many of these substances have demonstrated beneficial effects on cognitive performance and overall health. However, a thorough understanding of how these substances and their synergistic effects in the form of a supplement may benefit fundamental brain processes is currently lacking. In the current study, we will investigate the effects of a plant-based, nootropic supplement (https://uk.mindlabpro.com/) on perceptual decision-making (i.e. the ability to make rapid decisions based on sensory stimuli) in healthy adult participants.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2023
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 23, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 6, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2024
CompletedFirst Submitted
Initial submission to the registry
November 13, 2024
CompletedFirst Posted
Study publicly available on registry
November 14, 2024
CompletedNovember 14, 2024
November 1, 2024
5 months
November 13, 2024
November 13, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Perceptual decision-making performance
Choice accuracy and reaction times
Pre- and post- 60 days of supplementation
Secondary Outcomes (1)
Brain network interdependencies
Pre- and post- 60 days of supplementation
Study Arms (2)
Experimental group
EXPERIMENTALThis group will receive the nootropic supplement for 60 days.
Control group
PLACEBO COMPARATORThis group will receive a placebo supplement for 60 days
Interventions
Commercially available product: Mind lab pro
A cellulose commonly used as a bulking agent in supplement products
A computerised cognitive task involving rapid visual categorisation of images
Brain signals are recorded from a 64 channel EEG system during the cognitive task
Eligibility Criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Faculty of Biological sciences
Leeds, United Kingdom
Related Publications (1)
O'Reilly D, Bolam J, Delis I, Utley A. Effect of a Plant-Based Nootropic Supplement on Perceptual Decision-Making and Brain Network Interdependencies: A Randomised, Double-Blinded, and Placebo-Controlled Study. Brain Sci. 2025 Feb 21;15(3):226. doi: 10.3390/brainsci15030226.
PMID: 40149748DERIVED
Related Links
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ioannis Delis
University of Leeds
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
November 13, 2024
First Posted
November 14, 2024
Study Start
October 23, 2023
Primary Completion
March 6, 2024
Study Completion
June 1, 2024
Last Updated
November 14, 2024
Record last verified: 2024-11
Data Sharing
- IPD Sharing
- Will not share
No further investigations will take place using this data with anyone outside of the current research group