NCT06688474

Brief Summary

The goal of this study is to determine if the Otis Brux-Sensor Night Guard (OBSNG) can record the bite compression forces of participants with Bruxism. The main questions it aims to answer is:

  1. 1.Is it possible to design and miniaturize electrical hardware components small enough to fit onto the molar region of the custom night guard?
  2. 2.If successfully miniaturized, will we be able to capture bite compression force profiles and optimize data collection for analysis?

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Aug 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 5, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 18, 2024

Completed
13 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2024

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

November 8, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 14, 2024

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

March 3, 2026

Completed
Last Updated

March 3, 2026

Status Verified

January 1, 2026

Enrollment Period

2 months

First QC Date

November 8, 2024

Results QC Date

January 5, 2026

Last Update Submit

February 11, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean Nocturnal Clenching Force (% of Maximum Voluntary Clench)

    Clenching force measured by a sensor-enhanced mouth guard and expressed as a percentage of each participant's maximum voluntary clenching force established during calibration. Force was sampled at 4 Hz during overnight wear and summarized per participant as the mean nocturnal clenching force.

    Mean of nocturnal measurements across up to 21 nights of sensor wear

Study Arms (1)

Bruxism Cohort

2 male participants with diagnosed Bruxism will wear the device for 21 days, over a 6+ hour sleep period each night.

Eligibility Criteria

Age18 Years - 50 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

US participants only.

You may qualify if:

  • years of age
  • male and/or female
  • healthy with exception to being diagnosed with Bruxism.

You may not qualify if:

  • N/A

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Otis Dental

San Francisco, California, 94118, United States

Location

MeSH Terms

Conditions

Sleep Bruxism

Condition Hierarchy (Ancestors)

BruxismTooth DiseasesStomatognathic DiseasesParasomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Results Point of Contact

Title
Andrew Lee
Organization
Otis Dental, Inc

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 8, 2024

First Posted

November 14, 2024

Study Start

August 5, 2024

Primary Completion

October 18, 2024

Study Completion

October 31, 2024

Last Updated

March 3, 2026

Results First Posted

March 3, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations