NCT06683417

Brief Summary

This multi-center randomized trial (MCRT) will investigate the effectiveness of the VestAid application to provide equivalent or faster recovery from dizziness compared to standard-of-care delivery of vestibular rehabilitation exercises.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 8, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 12, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

January 15, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2025

Completed
Last Updated

November 12, 2024

Status Verified

November 1, 2024

Enrollment Period

12 months

First QC Date

November 8, 2024

Last Update Submit

November 8, 2024

Conditions

Keywords

mTBIvestibular rehabilitationvestibular disordertechnologyapplicationdizzinessbalance disorderimage processingeye gaze complianceVOR

Outcome Measures

Primary Outcomes (1)

  • Dizziness Handicap Inventory (DHI)

    A self report measure of dizziness (questionnaire)

    From enrollment weekly for 6 weeks.

Secondary Outcomes (1)

  • Secondary Endpoint

    From enrollment weekly for 6 weeks

Study Arms (2)

VestAid

EXPERIMENTAL

Use of VestAid tablet application to aid vestibular rehabilitation

Device: Vestibular Rehabilitation Aid

Standard of Care vestibular rehabilitation

ACTIVE COMPARATOR

Use of standard of care vestibular rehabilitation

Other: Standard of care vestibular rehabilitation

Interventions

The tablet-based VestAid system was developed to repair, restore and maintain vestibular-ocular function that is impaired in patients post-mTBI. Each participant\'s treating physical therapist will develop their own personalized exercise prescription. The physical therapist will be asked to recommend that the patients complete a home exercise program at least 2-3 times per day for 6 weeks. The exercise prescription will be placed on the VestAid by the physical therapist for the patient to follow. The patient is not able to modify the exercise, only the physical therapist can modify the exercises. Exercises will be modified based on patient\'s response and symptom reports. The physical therapist and study coordinator will receive an alert on the VestAid online dashboard if the patient\'s symptoms are greater than or equal to 8/10.

Also known as: VestAid
VestAid

Vestibular rehabilitation to include gaze stabilization exercises, optokinetic training, smooth pursuits and saccades

Standard of Care vestibular rehabilitation

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Snellen visual acuity (corrected) greater than 20/40
  • No more than 25dB hearing loss at 500,1000, 2000, and 4000 Hz
  • Ability to detect 4.31 using Semmes-Weinstein monofilament at the lower extremity
  • At least 40 degrees of neck yaw motion with only mild to moderate pain (6 or under on 0-10 numeric pain scale)
  • Internet access at home
  • No significant residual from past musculoskeletal or neuromuscular conditions
  • Ability ambulates unassisted
  • Diagnosed with a concussion or inner ear problem the last 30 days
  • Between 18-60 years of age
  • Can read and understand English
  • Has complaints of dizziness

You may not qualify if:

  • Greater then 30 days since diagnosis of concussion/mTBI or inner ear problem
  • No access to internet at home
  • Younger than 18 years of age or older than 60 years of age
  • Cannot read or understand English
  • No complaints of dizziness and/or balance deficits
  • Have significant neuropathy
  • Cannot see tablet clearly at 1 meter
  • Neck pain \>5 on a 10-point pain scale.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, 15219, United States

Location

Related Publications (6)

  • Whitney SL, Sparto PJ. Principles of vestibular physical therapy rehabilitation. NeuroRehabilitation. 2011;29(2):157-66. doi: 10.3233/NRE-2011-0690.

    PMID: 22027077BACKGROUND
  • Shepard NT, Telian SA. Programmatic vestibular rehabilitation. Otolaryngol Head Neck Surg. 1995 Jan;112(1):173-82. doi: 10.1016/S0194-59989570317-9.

    PMID: 7816453BACKGROUND
  • Gottshall K. Vestibular rehabilitation after mild traumatic brain injury with vestibular pathology. NeuroRehabilitation. 2011;29(2):167-71. doi: 10.3233/NRE-2011-0691.

    PMID: 22027078BACKGROUND
  • Hall CD, Herdman SJ. Reliability of clinical measures used to assess patients with peripheral vestibular disorders. J Neurol Phys Ther. 2006 Jun;30(2):74-81. doi: 10.1097/01.npt.0000282571.55673.ed.

    PMID: 16796772BACKGROUND
  • Essery R, Geraghty AW, Kirby S, Yardley L. Predictors of adherence to home-based physical therapies: a systematic review. Disabil Rehabil. 2017 Mar;39(6):519-534. doi: 10.3109/09638288.2016.1153160. Epub 2016 Apr 21.

    PMID: 27097761BACKGROUND
  • Mucha A, Collins MW, Elbin RJ, Furman JM, Troutman-Enseki C, DeWolf RM, Marchetti G, Kontos AP. A Brief Vestibular/Ocular Motor Screening (VOMS) assessment to evaluate concussions: preliminary findings. Am J Sports Med. 2014 Oct;42(10):2479-86. doi: 10.1177/0363546514543775. Epub 2014 Aug 8.

    PMID: 25106780BACKGROUND

MeSH Terms

Conditions

Brain ConcussionVestibular DiseasesDizziness

Condition Hierarchy (Ancestors)

Brain Injuries, TraumaticBrain InjuriesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesCraniocerebral TraumaTrauma, Nervous SystemHead Injuries, ClosedWounds and InjuriesWounds, NonpenetratingLabyrinth DiseasesEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Susan L Whitney, DPT, PhD, NCS, ATC, FAPTA

CONTACT

Chelsea J Manetta, PT, DPT, NCS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 8, 2024

First Posted

November 12, 2024

Study Start

January 15, 2025

Primary Completion

December 30, 2025

Study Completion

December 30, 2025

Last Updated

November 12, 2024

Record last verified: 2024-11

Locations