Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review

NCT06677281 | Completed

• 1 other identifier: COVID-PREG-2024-001
• Study Type: observational
• Target: 1
• Locations: 1 country
• Sites: 1

Brief Summary

This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health. The review focuses on key outcomes such as preterm birth, maternal complications, and neonatal health, utilizing comprehensive literature from peer-reviewed journals. By analyzing existing studies, we aim to identify trends and gaps in research regarding COVID-19 and pregnancy. This review is intended to inform healthcare providers and pregnant individuals about potential risks and considerations during the pandemic.

Conditions

COVID-19; Pregnancy Outcomes; Maternal Health; Neonatal Health

Outcome Measures

Primary Outcomes (1)

• Impact of COVID-19 on Maternal and Neonatal Outcomes

  This primary outcome measure evaluates the various maternal and neonatal outcomes associated with COVID-19 infection during pregnancy. Key metrics include rates of maternal morbidity, neonatal morbidity, preterm birth, low birth weight, and any documented complications during pregnancy, labor, and delivery. The systematic review aims to synthesize data from available studies to provide a comprehensive understanding of these outcomes and their implications for clinical practice.

  The review encompasses studies published from January 2020 to the present, with a focus on maternal and neonatal outcomes reported within the specified time frame.

Secondary Outcomes (1)

• Effects of COVID-19 on Pregnancy-Related Complications

  The review includes data from studies published between January 2020 and the present, focusing on complications reported throughout the pregnancy and at delivery.

Interventions

Systematic Review of COVID-19's Impact on Pregnancy Outcomes OTHER

This study is a systematic review of existing literature that examines the effects of COVID-19 on pregnancy outcomes, including maternal health, neonatal health, and obstetric complications. It synthesizes data from various studies to provide an overview of the potential risks associated with COVID-19 infection during pregnancy. This intervention does not involve any new clinical trials or direct patient interaction.

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of pregnant individuals diagnosed with COVID-19 as documented in various peer-reviewed studies. The review examines the impact of COVID-19 on pregnancy outcomes, including maternal health, delivery outcomes, and neonatal complications.

You may qualify if:

• Pregnant individuals diagnosed with COVID-19.
• Studies reporting pregnancy outcomes related to COVID-19 published between January 2020 and the present.
• Articles that include quantitative data on maternal and fetal outcomes.

You may not qualify if:

• Studies that do not report on COVID-19-related pregnancy outcomes.
• Non-peer-reviewed articles or grey literature.
• Research focusing on non-pregnant populations.

Sponsors & Collaborators

• Zahedan University of Medical Sciences: lead

Study Sites (1)

Zahedan University of Medical Sciences

Zahedan, Sistan and Baluchestan, Iran

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: November 5, 2024
• First Posted: November 6, 2024
• Study Start: May 3, 2024
• Primary Completion: August 15, 2024
• Study Completion: August 25, 2024
• Last Updated: November 6, 2024

Record last verified: 2024-11

Locations

IR (1)