NCT06675305

Brief Summary

Beetroot juice is a good source of nitrate (NO3-), which is a precursor of nitric oxide (NO) through the NO3- to nitrite (NO2-) to NO pathway (Lundberg et al., 2008). Consequently, it is thought that a minimum threshold may exist for dietary NO3- consumption of at least 5 mmol to enhance athletic performance (Senefeld et al., 2020). In turn, systematic reviews have documented that the use of beetroot juice supplementation enhances muscle strength and power-related attributes (Gonzalez et al., 2023), as well as performance in repeated high-intensity activity bouts (Alsharif et al., 2023; Dominguez et al., 2018). However, beetroot juice supplementation has been shown to have equivocal effects on neuromuscular performance specifically among individual sport athletes (e.g. taekwondo). Thus, the aim of this study was to determine the effects of acute beetroot juice ingestion (140 mL, 12.8 mmol NO3-) on neuromuscular performance in elite female taekwondo athletes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
7

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2022

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2022

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

November 4, 2024

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 5, 2024

Completed
Last Updated

November 5, 2024

Status Verified

November 1, 2024

Enrollment Period

2 months

First QC Date

November 4, 2024

Last Update Submit

November 4, 2024

Conditions

Keywords

nitratenitriteneuromusculartaekwondo

Outcome Measures

Primary Outcomes (1)

  • Simulated taekwondo Combat (actions/time)

    Simulated taekwondo combat were performed according to the guidelines of the World Taekwondo (WT), and participants were divided based in the Olympic weight categories (WT, 2016). All the combats were executed in an official octagonal and homologated competition area while an international referee (who doesn´t know the experimental treatments) arbitrated. Today the rules of WTF led to use electronic protectors as protecting of athletes and identify electronically the punctuations (Del Vecchio, Franchini, Del Vecchio, \& Pieter, 2011). Variables analyzed were attack time (AT), step time (ST), pause time (PT), period without attack (PWA = ST+PT), numbers of attacks (AN), the ratio for attack time and step time (R1 = AT/ST), and ratio for action time and step time (R2 = (AT+ST) /PT).

    1-week

Secondary Outcomes (4)

  • Changes in maximal jump height (cm)

    1-week

  • Reaction time (ms)

    1-week

  • Blood lactate concentrations (mmol·L-1)

    1-week

  • Rating of percevied exertion (RPE) (measured using scale 6-20 points)

    1-week

Study Arms (2)

Beetroot juice supplementation

EXPERIMENTAL

140 mL of beetroot juice (12.8 mmol of NO3-, Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) made from concentrates of beetroot juice (98%) and lemon juice (2%) (nutritional information (per 100 mL), energy: 373 kJ; fat: 0 g; carbohydrates: 18 g \[sugars: 17 g\]; protein: 3.7 g; salt: 0.48 g)

Dietary Supplement: Beetroot juice (James White, UK)

Placebo supplementation

PLACEBO COMPARATOR

140 mL of beetroot juice placebo without nitrates (0.08 mmol of NO3-, Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) made from concentrates of beetroot juice (98%) and lemon juice (2%) (nutritional information (per 100 mL), energy: 373 kJ; fat: 0 g; carbohydrates: 18 g \[sugars: 17 g\]; protein: 3.7 g; salt: 0.48 g)

Dietary Supplement: Placebo acute supplementation (James White, UK)

Interventions

One serving 140 mL of BJ (12.8 mmol of NO3-; Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) after an overnight fast and 2.5 h before initiating the testing session.

Beetroot juice supplementation

One serving 140 mL of BJ (0.04 mmol of NO3-; Beet-It-Pro Elite Shot, James White Drinks Ltd., Ipswich, UK) after an overnight fast and 2.5 h before initiating the testing session.

Also known as: Beetroot juice placebo
Placebo supplementation

Eligibility Criteria

Age16 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age between 16 to 40 years
  • Competed in international taekwondo competitions representing her national teams.
  • More than6 years of training experience (at least 3 sessions per week).
  • Female taekwondo athletes.

You may not qualify if:

  • Male taekwondo athletes.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universida Pontificia Comillas

Madrid, Spain

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 4, 2024

First Posted

November 5, 2024

Study Start

May 1, 2022

Primary Completion

July 1, 2022

Study Completion

August 15, 2022

Last Updated

November 5, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will not share

Locations