It is Accepted That Adenoid Hypertrophy is Related to Otitis Media With Effusion Incidence. Better Understanding of the Correlation Between the Relative Size of AH and the Incidence of Persistent OME May Provide Evidence to Support a More Standardized Approach to the Diagnosis and Treatment of OME.

NCT06674720 | Not Yet Recruiting

• 1 other identifier: Adenoid hypertrophy and MEE
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to further investigate the correlation between Site and size of adenoid hypertrophy and middle ear effusion in order to provide evidence for designing a more standardized approach to the diagnosis and treatment of OME.

Conditions

Adenoid Hypertrophy; Middle Ear Effusion

Outcome Measures

Primary Outcomes (1)

• Comparing presence of middle ear effusion in relation to site and size of adenoid hypertrophy

  The incidence of OME with each AH grade occurring in each age group of the sample size.

  Baseline

Eligibility Criteria

• Age: 1 Year - 16 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children age group (from 1 year old till 16 years old), male and female are included, with symptoms and signs of adenoid hypertrophy

You may qualify if:

• Children (until age of 16 years old).
• Patients with adenoid hypertrophy.
• Patients with OME.

You may not qualify if:

• Children known to have cleft palate, submucous cleft palate or other medical problems causing velopharyngeal insufficiency.
• Down's syndrome, septal deviation, primary ciliary dyskinesia (Kartagener's syndrome), previous head or ear trauma, or previous myringotomy with ventilation tube insertion
• Systemic medical problems interfering with surgery.
• Refusal of parents to participate.
• Craniofacial abnormalities.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (5)

• Mnatsakanian A, Heil JR, Sharma S. Anatomy, Head and Neck: Adenoids. 2023 Jul 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK538137/

  PMID: 30844164 BACKGROUND

• Khadgi A, Koirala K, Maharjan S, Chalise K, Dhungana I, Babu Karki B. Correlation of Conductive Hearing Impairment With Sizes of Adenoids in the Pediatric Age Group: An Observational Case-Control Study. Cureus. 2023 Aug 31;15(8):e44439. doi: 10.7759/cureus.44439. eCollection 2023 Aug.

  PMID: 37791228 BACKGROUND

• Niedzielski A, Chmielik LP, Mielnik-Niedzielska G, Kasprzyk A, Boguslawska J. Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance. BMJ Paediatr Open. 2023 Apr;7(1):e001710. doi: 10.1136/bmjpo-2022-001710.

  PMID: 37045541 BACKGROUND

• Ohuche IO, Iloanusi NI, Dike CM, Chime EN. Clinical presentation, radiographic findings, and treatment outcomes in children with adenoid hypertrophy in a paediatric outpatient clinic in Enugu, Nigeria. Ghana Med J. 2023 Sep;57(3):204-209. doi: 10.4314/gmj.v57i3.7.

  PMID: 38957679 BACKGROUND

• Galic MZ, Klancnik M. ADENOID SIZE IN CHILDREN WITH OTITIS MEDIA WITH EFFUSION. Acta Clin Croat. 2022 Feb;60(3):532-539. doi: 10.20471/acc.2021.60.03.25.

  PMID: 35282481 BACKGROUND

MeSH Terms

Conditions

Otitis Media with Effusion

Condition Hierarchy (Ancestors)

Otitis Media; Otitis; Ear Diseases; Otorhinolaryngologic Diseases

Study Officials

• Mohammed Ahmed Salem, Professor

  Assuit University hospital

  STUDY DIRECTOR

Central Study Contacts

Esraa A Mohamed, Bachelor's

CONTACT

+201122736706; esraa.aboalqasem@gmail.com

Mohamed O Gad, Professor

CONTACT

+201227006258; Omargad@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: September 30, 2024
• First Posted: November 5, 2024
• Study Start: May 1, 2025
• Primary Completion: May 1, 2025
• Study Completion (Estimated): December 1, 2027
• Last Updated: January 17, 2025

Record last verified: 2025-01